ID A9UWY8_MONBE Unreviewed; 1094 AA.
AC A9UWY8;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=MONBRDRAFT_24613 {ECO:0000313|EMBL:EDQ90124.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ90124.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ90124.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991548; EDQ90124.1; -; Genomic_DNA.
DR RefSeq; XP_001744891.1; XM_001744839.1.
DR AlphaFoldDB; A9UWY8; -.
DR STRING; 81824.A9UWY8; -.
DR EnsemblProtists; EDQ90124; EDQ90124; MONBRDRAFT_24613.
DR GeneID; 5890294; -.
DR KEGG; mbr:MONBRDRAFT_24613; -.
DR eggNOG; KOG1001; Eukaryota.
DR InParanoid; A9UWY8; -.
DR OMA; KVEPWSN; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IBA:GO_Central.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR CDD; cd18008; DEXDc_SHPRH-like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45626:SF22; DNA REPAIR PROTEIN RAD5; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 6..35
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 440..677
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 882..920
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 909..1088
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 38..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1094 AA; 120373 MW; 5ADD96EA3FD08E78 CRC64;
MAQPQPPEQW ACPACTLLNN VLLPRCTLCG AARPASINAK RPASSLDRLQ APSRKISRNK
PKLSTASSQP QSPDTSAAAK GAGSGANTTA VATGAASASK NRPKSGSKAS VKAGKTGTKA
NPTQRRGSDR FGTQRDGTPT YRALHHLYEQ GRSATEQIRA PFEHGPWPKV IGECIVQGIA
NRSGRGLLSA GDALRFSYSL PDKRHSHHGT VTFGRDHELG TLSTQASLWL GPLLAAGAVR
LTGTAIYLKN PEKLSFSDTI DISITIYGSP VAFLQRPDEA FAGNVATEGL EVTIITRAWQ
ACFTNCGFID ANAHGGPALR RPSTADAATD STQADETADR DGAQDEEGEE NNDLQFICEQ
LGLDQTLMPT LEPHACVKST LRPYQKQALW WLVSREQLSA SARDTGRERQ LHPLWQEMRF
ASGDAFFWKQ AGGRVSVYFP HASQQARGGI LADAMGLGKT VQSLALVATQ PAPPSFIASH
HDSAASNASS AEPLLGAPTQ RARDSLSLDE FLDARPTRRS SDGSEAASAV GNALASSNTS
GIPGSKATLI VCPVSLLSQW EEEVHQHLEG MKVLPYHAQR STVTPALIWT EYDVVLTTYG
VVTSEHMQHL RGQTSLLFGT HFWRIILDEG HMIRNRNTAG ARACHELSAR NRWVLTGTPI
QNRLEDVYSL IRFLRVEPYA HFSYWRQHVQ EPFERDEDAG ISALQKILAP LLLRRTKHTK
DETGSPIVQL PSSSVEVLML EFSSAEREFY DAIFQRSKNK FDEFQAAGKV LNNYANILEL
LLRLRQACDH PFLTLRNMTQ EEEAAREDKR LRTQARQGVF SDIDTLVAKF MSDSRQGNAS
LRADHVATMA EDLRYLLQRS SHGASAQQNQ ETKATEQAPP ECSVCLDTID EPVVTPCAHY
GCRVCMENAV DNFHECPLCR KPLQRSSLFR IQAPDPDVES AATAPPNEDD RQHWLSSSKL
KALLADLDAA TQQPDRPKVI VFSQWTSMLD LIEVFLMTLR TGGVGLNLTA ASHVILVDPW
WSPAVEAQAI DRVHRIGQDK PVTIKRYIMR DSIEERILAL QKRKRALVHS ALTRNATERQ
AERMSDLKLL FGQF
//
