ID   A9V1R6_MONBE            Unreviewed;       426 AA.
AC   A9V1R6;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=DNA/RNA-binding protein Kin17 WH-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MONBRDRAFT_8991 {ECO:0000313|EMBL:EDQ88608.1};
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88608.1, ECO:0000313|Proteomes:UP000001357};
RN   [1] {ECO:0000313|EMBL:EDQ88608.1, ECO:0000313|Proteomes:UP000001357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- SIMILARITY: Belongs to the KIN17 family.
CC       {ECO:0000256|ARBA:ARBA00008517}.
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DR   EMBL; CH991554; EDQ88608.1; -; Genomic_DNA.
DR   RefSeq; XP_001746712.1; XM_001746660.1.
DR   AlphaFoldDB; A9V1R6; -.
DR   STRING; 81824.A9V1R6; -.
DR   EnsemblProtists; EDQ88608; EDQ88608; MONBRDRAFT_8991.
DR   GeneID; 5891964; -.
DR   KEGG; mbr:MONBRDRAFT_8991; -.
DR   eggNOG; KOG2837; Eukaryota.
DR   InParanoid; A9V1R6; -.
DR   OMA; RMTDFIE; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0006974; P:DNA damage response; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IBA:GO_Central.
DR   CDD; cd13155; KOW_KIN17; 1.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 1.10.10.2030; DNA/RNA-binding protein Kin17, conserved domain; 1.
DR   InterPro; IPR019447; DNA/RNA-bd_Kin17_WH-like_dom.
DR   InterPro; IPR037321; KIN17-like.
DR   InterPro; IPR038254; KIN17_WH-like_sf.
DR   InterPro; IPR041330; KN17_SH3.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041995; KOW_KIN17.
DR   InterPro; IPR014722; Rib_uL2_dom2.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   PANTHER; PTHR12805:SF0; DNA_RNA-BINDING PROTEIN KIN17; 1.
DR   PANTHER; PTHR12805; KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG; 1.
DR   Pfam; PF10357; Kin17_mid; 1.
DR   Pfam; PF18131; KN17_SH3; 1.
DR   SMART; SM01253; Kin17_mid; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT   DOMAIN          52..178
FT                   /note="DNA/RNA-binding protein Kin17 WH-like"
FT                   /evidence="ECO:0000259|SMART:SM01253"
FT   DOMAIN          369..396
FT                   /note="KOW"
FT                   /evidence="ECO:0000259|SMART:SM00739"
FT   REGION          255..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          274..304
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   426 AA;  48225 MW;  A1AD909CE426948B CRC64;
     MPKNGFLTPK AIGNRIKSKG LQKLRWYCQV CQKQCRDANG FKCHVMSEPH QRQMLLVGQN
     TGKVIDEFSQ EFRDGFLTLL RRSYNTRRVM ANSVYNAYIG DKEHIHMNAS KWQSLTEFVK
     YLGREGYCLV DETPKGWYIQ WIDRDPETLE RQARLRRMEA SRKDEADRQA EMLEAQMERD
     RQAVEASGVS IEETEKTALL RESEDDKVVV SLKRGPTLLD ATTTATAEGP LPGAALDELA
     GAEEDAHALL GIKKKAKRTS PDARGKARPG KPLSALEQIR LDNERAKRAK LEREQERLAR
     EQQARPDRVE NWLYPGLVVK VINKKVLDGR YYKCKGVVLS LVDDFVAKVK LLDSKATLKL
     DQDFLETVIP KPGGVVLVVN GPLRGAEAVV EEILEKDFSC RVQLTSGPTK GDTVRLPYED
     ICRLDA
//