ID A9V2A0_MONBE Unreviewed; 712 AA.
AC A9V2A0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDQ88339.1};
GN ORFNames=MONBRDRAFT_9161 {ECO:0000313|EMBL:EDQ88339.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ88339.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ88339.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991555; EDQ88339.1; -; Genomic_DNA.
DR RefSeq; XP_001746932.1; XM_001746880.1.
DR AlphaFoldDB; A9V2A0; -.
DR STRING; 81824.A9V2A0; -.
DR EnsemblProtists; EDQ88339; EDQ88339; MONBRDRAFT_9161.
DR GeneID; 5892216; -.
DR KEGG; mbr:MONBRDRAFT_9161; -.
DR eggNOG; KOG1000; Eukaryota.
DR InParanoid; A9V2A0; -.
DR OMA; WHHEICK; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0043596; C:nuclear replication fork; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0031297; P:replication fork processing; IBA:GO_Central.
DR CDD; cd18010; DEXHc_HARP_SMARCAL1; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR010003; HARP_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45766; DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45766:SF3; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51467; HARP; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 1..79
FT /note="HARP"
FT /evidence="ECO:0000259|PROSITE:PS51467"
FT DOMAIN 131..285
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 410..564
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 547..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 79875 MW; 77DCD7B7563C2140 CRC64;
MARTGEGLHV HAALRADGCS ASISCSFRRP IIQALRAHRG YFDRTCRAWV VPLAQYRALL
IQFERLDLGP ERLMIKAIPD VVLRLTEHPD WQRQATQHQS FSATELLAIT GTRLPRRLVH
KMMPYQRAGV ACAIERGGRV LWSDEMGLGK TVSSLATAAY YQAEWPLLVV CPSSLKLTWH
HEICKWLQID ESAIGVVSSK KSPMNKLVTI LSYDLARNLH EHLTSADFQV IIADESHYLK
NGKAARTKAL MPLLHKAKRV LLLSGTPALS RPIELYQQLH ALAPRLFRSE VAFGIRYCNS
QLTAFGWRHD GSCNQDELHC VLERLVMIRR VKAAVLTDLP PKTRQEVYVQ ADPAPLRALK
AIMQKRKALE RQLASLHGSQ RAQGERALQA LTTEAYGLTG EAKIKGCLRY LEDLMNHDGK
LLIFAHHKTL LDELATFLCQ RQLRHIRIDG STPTHLRQQL CNSFQDDVLC RVAVLSITTA
GTGLTLHAAN TVVFAELYWN PGHLYQAEDR AHRVGQRHNV NVRYLLCPGT LDDVMWSQLQ
RKAKIVQRAM AGASTTQPKP EEPSNKRAHT NQAHGNKPRS QPDDDRCNEQ HDHLDLAEQP
DVLVVDEDSG DKENEASPPR HRQEPVTEAQ EAPRSFEDFD DWTDAVAVAE AVEQRVGLPN
PARKLTQSSP PAAVEASEFQ IQAVCPLCTQ SVLAAQLPLH VQSCEDVAWL EQ
//
