ID A9V5D1_MONBE Unreviewed; 466 AA.
AC A9V5D1;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=Nucleotidyl transferase domain-containing protein {ECO:0000259|Pfam:PF00483};
GN ORFNames=MONBRDRAFT_33433 {ECO:0000313|EMBL:EDQ87353.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ87353.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ87353.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000256|ARBA:ARBA00007274}.
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DR EMBL; CH991560; EDQ87353.1; -; Genomic_DNA.
DR RefSeq; XP_001747966.1; XM_001747914.1.
DR AlphaFoldDB; A9V5D1; -.
DR STRING; 81824.A9V5D1; -.
DR EnsemblProtists; EDQ87353; EDQ87353; MONBRDRAFT_33433.
DR GeneID; 5893101; -.
DR KEGG; mbr:MONBRDRAFT_33433; -.
DR eggNOG; KOG1460; Eukaryota.
DR InParanoid; A9V5D1; -.
DR OMA; MPVPNWW; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd06428; M1P_guanylylT_A_like_N; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR22572:SF104; MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE ALPHA; 1.
DR PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 59..307
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 50894 MW; 72B4E6ECF1FE0F9D CRC64;
MDTSPYKSST PPSSSTNLDA VMGTTPSGAK THSRKRSISV KMGEDTADLQ SKHSFQKIKT
VILVGGVMQG TPFRPLSFKC PVPLLPIANQ PSIMHIMSKA AAVKGMAEIL IIGGYQEADF
ASFIRDAERE LGLPVRYLQE YTQLGTAGGM YHFRDLVRRG NPDAVFVVHG NVCSDVDFNE
LLTFHSCVGD GLHTTMLTVK AREDQAKQYG CVVADKAFSV VHYVEKPSSF VSEHINTGIY
VMSTAVFDTI KSIFRSTADG IQERIMFETD VVPRLVNNGH LFAFPSTAFW SQVKTAGSAV
YANRHYLEQY ARHEPERLAR SSEEGFKVVG NVVVDPSASV HPSAKLGPNV SVGPNVKIHA
GARVKDTILL DSVEMAEQSC AFNSVIGWNS TLGRWARVEG LPVTADPNDP STHISQPPIF
NTDGKLEPSI AVLGEEVEVG DEILIQHCLV LPHKQLTESR KNEIIL
//
