ID A9V9K8_MONBE Unreviewed; 460 AA.
AC A9V9K8;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDQ85685.1};
GN ORFNames=MONBRDRAFT_34097 {ECO:0000313|EMBL:EDQ85685.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ85685.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ85685.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR EMBL; CH991571; EDQ85685.1; -; Genomic_DNA.
DR RefSeq; XP_001749400.1; XM_001749348.1.
DR AlphaFoldDB; A9V9K8; -.
DR STRING; 81824.A9V9K8; -.
DR EnsemblProtists; EDQ85685; EDQ85685; MONBRDRAFT_34097.
DR GeneID; 5894689; -.
DR KEGG; mbr:MONBRDRAFT_34097; -.
DR eggNOG; KOG1479; Eukaryota.
DR InParanoid; A9V9K8; -.
DR OMA; GSPWTTK; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IBA:GO_Central.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF10; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 242..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 50229 MW; 41C484486B49CDA0 CRC64;
MGHPEEAGVA EPLLAIPEDN VVVHRSSDRS VVGFLYFLFF LEGIGSLFPW NAFITVTSYF
DDVLAGTNYA SSYENYFSFS FQGASIIFIL LAMRYKQRIN VHTRILAPLV IEVIVFSSVT
VISKIPGLST NAFMSITIGQ TVAAGAAGAF LQSGLFGLAG VMPEAYVHAL MNGQALGGVI
VAGLNLVSLG VSGTSQPREA AFLFFILSVV VLLCCFVGYV LLMRHPLVIS NLEKADAARI
ASTQASPRKN PDMSSSVNQT KRDRKSLKRY RSYLHSEDGA ILSPFRKAWL PCVMVFCVFW
ITLSIFPAIS ASVSSTSPYE EWRSWFVPVC VFFLFNFGDL IGRLLTWWKP WPETANYRKL
PIPVLARVLF VPLFALCNVA NADYVLFKND AFPALFMLAV GISNGYLGTM CMMIAPSLVP
PGDAESVGQF SVLLLNLGLL SGSLTGFGLK AAICKCNPFK
//
