ID A9VBZ3_MONBE Unreviewed; 421 AA.
AC A9VBZ3;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=MONBRDRAFT_29736 {ECO:0000313|EMBL:EDQ84889.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ84889.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ84889.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH991579; EDQ84889.1; -; Genomic_DNA.
DR RefSeq; XP_001750230.1; XM_001750178.1.
DR AlphaFoldDB; A9VBZ3; -.
DR STRING; 81824.A9VBZ3; -.
DR EnsemblProtists; EDQ84889; EDQ84889; MONBRDRAFT_29736.
DR GeneID; 5895541; -.
DR KEGG; mbr:MONBRDRAFT_29736; -.
DR eggNOG; KOG1842; Eukaryota.
DR InParanoid; A9VBZ3; -.
DR OMA; PICMTDF; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036531; Rbsn_Rab-bd_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF140125; Rabenosyn-5 Rab-binding domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001357};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 102..191
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 322..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 46417 MW; 138AEDAEACB52D5D CRC64;
MEVAAGFVCP SCFKDLGNLE SLEKHFAAGC KGPSAGKTGP GTKGNRLAKL LKLKSADDET
APGALGAAAA PNPADDPAYL THVEFEPQTI DFERNIIPWV DGKIIKACPE CGKKFSLTRR
QHHCRLCGSV LCDDCSLALE ANVAIALTVP PELPGKKQRL SHEQKLTLLR ESLVIPGEVI
RICPFCHQSL HTYAIATASV FPICNAANVK SKCKQPQYPI TGSSSKPIRA TAAVGSYESV
AEEFQAISAD LLVIEKQCRV VAGAIKKEDA DKFPSSLRLH AAITQQWRTF IQMTKGTRMT
LPPLADVKKI ALEREKARQE AEERERQLRL QQQREREQAE KEAAAIRARR AARKEKEPRR
NAPTPPTAAA VPVNADTLML IREQRTYIMR CIKDARRRNA QDEVNMLQAQ LQELEVIMGQ
S
//
