ID A9VEK7_MONBE Unreviewed; 495 AA.
AC A9VEK7;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN ORFNames=MONBRDRAFT_30655 {ECO:0000313|EMBL:EDQ84034.1};
OS Monosiga brevicollis (Choanoflagellate).
OC Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX NCBI_TaxID=81824 {ECO:0000313|EMBL:EDQ84034.1, ECO:0000313|Proteomes:UP000001357};
RN [1] {ECO:0000313|EMBL:EDQ84034.1, ECO:0000313|Proteomes:UP000001357}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX1 / ATCC 50154 {ECO:0000313|Proteomes:UP000001357};
RX PubMed=18273011; DOI=10.1038/nature06617;
RG JGI Sequencing;
RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT metazoans.";
RL Nature 451:783-788(2008).
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DR EMBL; CH991690; EDQ84034.1; -; Genomic_DNA.
DR RefSeq; XP_001751154.1; XM_001751102.1.
DR AlphaFoldDB; A9VEK7; -.
DR STRING; 81824.A9VEK7; -.
DR EnsemblProtists; EDQ84034; EDQ84034; MONBRDRAFT_30655.
DR GeneID; 5896415; -.
DR KEGG; mbr:MONBRDRAFT_30655; -.
DR eggNOG; KOG1343; Eukaryota.
DR InParanoid; A9VEK7; -.
DR Proteomes; UP000001357; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001357}.
FT DOMAIN 122..344
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 53155 MW; 3D1615B57337FA90 CRC64;
MFFSAPVTPR TSHPTSRCGS PTSTHLSDYE RYPIIADSLT GLPAPSARTP KLSRSSRSSP
AFTVDMLNKA ARMVTMTKQL RAVEQARAVD ALPTAALTEL ARTFSWTPTD NSSGALPPVV
PAIMQGLVDC KLWNRCTPEA PRHASDDELQ LVHTAEYVRH YGSLSTPAPQ ATINGFAGDD
RVYISSNYSE TAASTRCAAA AVIDATRLVA EGRAKNAVVL AQPAGRLVGQ SGPPRGLGVF
NNIAIAARHA LQTQTAQRIA ILDWGRERAA PLTQLFASDP RVVVASIFRH DRRGVADATA
ATTYTGLTNN IVNVPLPQDV RVSDADYLAA FRSAVVPILS ERCPSAGYAH LTQSLMGVSH
GRIVLVLEDT PPTTLSESIA GLEGCLHALL GDDLSALPYP DVSPNEATVA VLEQLWMVHR
RAYGTLETTA AYRHFSPQEY MTMQRQREDE ELDATVALAS LSMMAVPEMP SEEAEEEARA
ASSDVTSGSD GQYMV
//
