ID A9WC07_CHLAA Unreviewed; 583 AA.
AC A9WC07;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ABY36959.1};
GN OrderedLocusNames=Caur_3781 {ECO:0000313|EMBL:ABY36959.1};
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY36959.1, ECO:0000313|Proteomes:UP000002008};
RN [1] {ECO:0000313|Proteomes:UP000002008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC {ECO:0000313|Proteomes:UP000002008};
RX PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT "Complete genome sequence of the filamentous anoxygenic phototrophic
RT bacterium Chloroflexus aurantiacus.";
RL BMC Genomics 12:334-334(2011).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP000909; ABY36959.1; -; Genomic_DNA.
DR RefSeq; WP_012259612.1; NC_010175.1.
DR RefSeq; YP_001637348.1; NC_010175.1.
DR AlphaFoldDB; A9WC07; -.
DR STRING; 324602.Caur_3781; -.
DR EnsemblBacteria; ABY36959; ABY36959; Caur_3781.
DR KEGG; cau:Caur_3781; -.
DR PATRIC; fig|324602.8.peg.4247; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_4_2_0; -.
DR InParanoid; A9WC07; -.
DR Proteomes; UP000002008; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF16; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000002008}.
FT DOMAIN 294..514
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 66459 MW; B81393E91071B7FF CRC64;
MSEQEMTPVQ RKQAPGDKPT GIKLVAPARP NERAGEIRFV EMPREKTPRL DVLVLNPPSP
DGDLFLRDIA RVGRRTRDGI IWPQTALAQI AAVVKEAGYS VEVIDAIGLM MDWKSFEKYM
WEKKPRYMII HATAPTLTND MRTTFIGKAV GTITMAIGTH VTPMTRETLE SYPTLDIVVR
GEPELTIVDV IRTIDRVVEE ERAADTVPVG NPDLTPPWRK LPFPDASYLT TRGRFLGVHP
KIIAKALRET LGVGYRDEHG EVRINPDRPF IEDLDTLPIP LHDQLPWQRY KVPIVGGPYT
FVLTSRGCPA GCRYCIKHVT YQSSVRHRSP HHVLQEMVML KEMGMHHIHF EADLFTVKKE
FVYDLCHTII KEGLKLRWSC NSRVDFVDED ELRLMRKAGC FMIAWGLESG SEEVLKRARK
GTTVKRIEET IAASHRAGIM NWGYFIIGLP GETVETIQQT IALSKRLPLD IALFHIATPY
PGTPFYYEAV ANGWIRMNQW EDYDMYSHTV LNYPHLSSAD LEYWAKRAAR EWSLRPRPIM
TFLKGAANPE TWGQLWQIGV NHLKWIGGSL RNEGLRRLSG SSM
//
