ID K6PF_CHLAA Reviewed; 356 AA.
AC A9WCU2;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 01-MAY-2013, entry version 41.
DE RecName: Full=6-phosphofructokinase;
DE Short=Phosphofructokinase;
DE EC=2.7.1.11;
DE AltName: Full=Phosphohexokinase;
GN Name=pfkA; OrderedLocusNames=Caur_0258;
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexi; Chloroflexales; Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O.,
RA Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Pierson B.K.,
RA Blankenship R.E., Richardson P.;
RT "Complete sequence of Chloroflexus aurantiacus J-10-fl.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC fructose 1,6-bisphosphate.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the phosphofructokinase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP000909; ABY33511.1; -; Genomic_DNA.
DR RefSeq; YP_001633900.1; NC_010175.1.
DR ProteinModelPortal; A9WCU2; -.
DR STRING; 324602.Caur_0258; -.
DR EnsemblBacteria; ABY33511; ABY33511; Caur_0258.
DR GeneID; 5824865; -.
DR KEGG; cau:Caur_0258; -.
DR PATRIC; 21411026; VBIChlAur28763_0298.
DR eggNOG; COG0205; -.
DR HOGENOM; HOG000248869; -.
DR KO; K00850; -.
DR OMA; TVPLERY; -.
DR ProtClustDB; CLSK983903; -.
DR BioCyc; CAUR324602:GIXU-261-MONOMER; -.
DR UniPathway; UPA00109; UER00182.
DR GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:HAMAP.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR HAMAP; MF_00339; Phosphofructokinase; 1; -.
DR InterPro; IPR012003; ATP_PFK_prok.
DR InterPro; IPR012829; PFK.
DR InterPro; IPR022953; Phosphofructokinase.
DR InterPro; IPR015912; Phosphofructokinase_CS.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR Pfam; PF00365; PFK; 1.
DR PIRSF; PIRSF000532; ATP_PFK_prok; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Ppfruckinase; 1.
DR TIGRFAMs; TIGR02483; PFK_mixed; 1.
DR PROSITE; PS00433; PHOSPHOFRUCTOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase;
KW Magnesium; Metal-binding; Nucleotide-binding; Reference proteome;
KW Transferase.
FT CHAIN 1 356 6-phosphofructokinase.
FT /FTId=PRO_1000079308.
FT NP_BIND 25 29 ATP (By similarity).
FT NP_BIND 167 171 ATP (By similarity).
FT NP_BIND 184 200 ATP (By similarity).
FT ACT_SITE 140 140 Proton acceptor (By similarity).
FT METAL 198 198 Magnesium; via carbonyl oxygen (By
FT similarity).
FT METAL 200 200 Magnesium (By similarity).
FT BINDING 175 175 Substrate (By similarity).
FT BINDING 272 272 Substrate (By similarity).
FT BINDING 278 278 Substrate (By similarity).
FT BINDING 281 281 Substrate (By similarity).
SQ SEQUENCE 356 AA; 37703 MW; C8B7B858A07B643C CRC64;
MASKKQRIGV LTSGGDAPGL NAVIRAVVKS ASGLGWEVIG IHDGFEGLLG TKSYRVLTNA
DVQGLLPRGG TILRTTNKGH FGPRRSDELS EADPYVRAVK AIEEMGLRAL ITIGGEGTQR
IALELHKLGA PVIGVPKTID NDLAGTDRTF GFDTALQVAT DAIDRLHTTA ASHNRVMVLE
VMGRHTGWIA LHAGLAGGAD VILIPEIPFS IERVAEKVMA RDQQGSSFSI IVVAEGARPR
GGSEMYIAEG RLGGIGHWVG EQLEKLTAKE VRVVVLGHLQ RGGSPSPYDR LLSTRYGAAA
VQAAARGIYG EMVALRGQDI VTVPLAEACG HLNRVRPHSD LVLCARSLGI AFGDEL
//
