ID A9WF07_CHLAA Unreviewed; 440 AA.
AC A9WF07;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:ABY35322.1};
GN OrderedLocusNames=Caur_2110 {ECO:0000313|EMBL:ABY35322.1};
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY35322.1, ECO:0000313|Proteomes:UP000002008};
RN [1] {ECO:0000313|Proteomes:UP000002008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC {ECO:0000313|Proteomes:UP000002008};
RX PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT "Complete genome sequence of the filamentous anoxygenic phototrophic
RT bacterium Chloroflexus aurantiacus.";
RL BMC Genomics 12:334-334(2011).
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP000909; ABY35322.1; -; Genomic_DNA.
DR RefSeq; WP_012257976.1; NC_010175.1.
DR RefSeq; YP_001635711.1; NC_010175.1.
DR AlphaFoldDB; A9WF07; -.
DR STRING; 324602.Caur_2110; -.
DR EnsemblBacteria; ABY35322; ABY35322; Caur_2110.
DR KEGG; cau:Caur_2110; -.
DR PATRIC; fig|324602.8.peg.2392; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_2_0; -.
DR InParanoid; A9WF07; -.
DR Proteomes; UP000002008; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002008}.
FT DOMAIN 332..428
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 440 AA; 48401 MW; DC04670B2695F822 CRC64;
MFHELMNRIH GRTAKVGVIG LGYVGLPLAE RAGRVGFSVL GFDVSPMRVA QVNRGESYIG
DVSSDALATL REAGRIEATT DVRRMAECDI LVICVPTPLN ATREPDMRFV EAASENVAAS
IRPGQLVILE STTYPGTTRE LIMPRIERSG LKVGEQIFLA FSPERIDPGQ TSSKGYSVEN
TPKVVGGVTP HCTELAGAFY GYITSRVVPV SSPDVAELTK LFENIFRAVN IALVNELALL
CDRMGIDVWE VIDAAATKPY GFMKFTPGPG LGGHCIPIDP FYLTWKARAY DLTTRFIELA
GEINSQMPRH VHDLVVRALN RARKPLNGST ILLLGIAYKP DVDDYRESPA FKVYDLLTAD
GATVIPCDPH ITQFELHDGR CMQTVPLTDE LLRQCDCAVI ITNHRAFDYE RIVTLAPAIV
DTRNATRNIQ GELRTKITVL
//
