ID A9WFA0_CHLAA Unreviewed; 1115 AA.
AC A9WFA0;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Peptidase S8 and S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:ABY36084.1};
GN OrderedLocusNames=Caur_2885 {ECO:0000313|EMBL:ABY36084.1};
OS Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY36084.1, ECO:0000313|Proteomes:UP000002008};
RN [1] {ECO:0000313|Proteomes:UP000002008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC {ECO:0000313|Proteomes:UP000002008};
RX PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT "Complete genome sequence of the filamentous anoxygenic phototrophic
RT bacterium Chloroflexus aurantiacus.";
RL BMC Genomics 12:334-334(2011).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; CP000909; ABY36084.1; -; Genomic_DNA.
DR RefSeq; WP_012258737.1; NC_010175.1.
DR RefSeq; YP_001636473.1; NC_010175.1.
DR AlphaFoldDB; A9WFA0; -.
DR STRING; 324602.Caur_2885; -.
DR EnsemblBacteria; ABY36084; ABY36084; Caur_2885.
DR KEGG; cau:Caur_2885; -.
DR PATRIC; fig|324602.8.peg.3248; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_281153_0_0_0; -.
DR InParanoid; A9WFA0; -.
DR Proteomes; UP000002008; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR001434; OmcB-like_DUF11.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF01345; DUF11; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000002008};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 193..634
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 442..521
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 685..781
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT DOMAIN 787..856
FT /note="DUF11"
FT /evidence="ECO:0000259|Pfam:PF01345"
FT REGION 209..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..232
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 202
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 286
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 598
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1115 AA; 117084 MW; 4F81C1817641168C CRC64;
MSRLFSRNYL VALTLLLSLV LAGILPLRPV EAQPRPDRPT PGTPLTIEPL TASSREDVAV
NKNLALSRDG TLASVFLKID SPSLASFMAQ NGITDINAPA AQDYLRQLNA ELDALIAQAQ
QRIPGLIVTH RFDLIIGGVS VAAPVSHLDQ LRRLPNVVEV INDRIERIET YRTPAFIGAT
TAWNRGGGSA FAGEGVIFGV LDSGVWPEHP SFSDPDPLGK PYAPPPPAPG NPGGLRACNF
GSATPGDAPF TCNNKLIGSY RFMSAYDFFV GTQPYEFRSG RDDDGHGTHT ASTAAGNRGV
PASDGSRVFG TISGIAPRAY IVNYKVCGEL GCFTTDSAAA VQQAIRDGVH VINFSISGGT
NPYSDIASLA FLDAYNAGIL VSASAGNSGP APDTVNHREP WVATVGASTS DRSYLSTLTV
QGSSGTFTAV GASSGAGIST PAPVVVNTTD PLCLNPAAAG TFTGQIVVCE RGIIARVAKS
ANVAAGGAIG MILYNPTPSS LDADFHSIPT VHIQNTDGSA LLAFLTANPG ATATFTPGAP
GPIQGDVMAG FSSRGGPGQT LGISKPDVTA PGVNILAGYT AIEYGQAVPQ FAFLSGTSMS
SPHNAGAAIL LKWLNPTWTP GQIKSALMTS AKAAGVYKED GVTRFTPFDA GSGRIDLRKA
WDPGLTFDET GANYLALQNE LWKANYPSLY VPRMPGLITV SRTVREVSGY NSFYKSTISY
QAGQPRDFKV IVPKEFFVPA NGTYTFNITV DARDVPLGQV RHAVVIFTER NGCQVRFPVT
IVRGEPDIRM EKQCDPATLA LRGTTDCTIS ITNTTFNDVT VTLNDTMPKQ LKLVSGSVTG
GATETSNGLT FSGTLTGASP PNISAGRLTF NGYLSLASLG ASPNVSLGDE TIANFTLSRP
FVFGGQTYNT IGMVSNGYAV IGGGTAADVQ YINRTFPNPA RPNNTLGAFW TDLDGSAGGG
YYAYLVGFGP CSNPANACWL ILEWENAPNW GDGELNTFQI WIGLNGVEDI TYSYGPTLSD
GDSGYVTVGA ENAFGNRGAN IYSNDGFGPI VGTIPTANSN DVYIATTPGT PGQTITIGFR
AQGVRLGRWT NYAELTSPSF FGTYIDPFSG EVVRP
//
