ID A9WX94_BRUSI Unreviewed; 831 AA.
AC A9WX94;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Type IV secretion system protein virB4 {ECO:0000256|ARBA:ARBA00023635};
GN OrderedLocusNames=BSUIS_B0070 {ECO:0000313|EMBL:ABY39097.1};
OS Brucella suis (strain ATCC 23445 / NCTC 10510).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=470137 {ECO:0000313|EMBL:ABY39097.1, ECO:0000313|Proteomes:UP000008545};
RN [1] {ECO:0000313|EMBL:ABY39097.1, ECO:0000313|Proteomes:UP000008545}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23445 / NCTC 10510 {ECO:0000313|Proteomes:UP000008545};
RA Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C.,
RA Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S.,
RA Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M.,
RA Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H.,
RA Bruce D., Detter C., Munk C., Brettin T.S.;
RT "Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC {ECO:0000256|ARBA:ARBA00006512}.
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DR EMBL; CP000912; ABY39097.1; -; Genomic_DNA.
DR RefSeq; WP_006073208.1; NC_010167.1.
DR AlphaFoldDB; A9WX94; -.
DR KEGG; bmt:BSUIS_B0070; -.
DR HOGENOM; CLU_008341_3_0_5; -.
DR Proteomes; UP000008545; Chromosome II.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004346; CagE_TrbE_VirB.
DR InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR043964; P-loop_TraG.
DR NCBIfam; TIGR00929; VirB4_CagE; 1.
DR PANTHER; PTHR30121:SF10; BLR3062 PROTEIN; 1.
DR PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR Pfam; PF03135; CagE_TrbE_VirB; 1.
DR Pfam; PF19044; P-loop_TraG; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 185..388
FT /note="CagE TrbE VirB component of type IV transporter
FT system central"
FT /evidence="ECO:0000259|Pfam:PF03135"
FT DOMAIN 452..566
FT /note="TraG P-loop"
FT /evidence="ECO:0000259|Pfam:PF19044"
SQ SEQUENCE 831 AA; 94527 MW; 3C8D3695FA849CE4 CRC64;
MGAQSKYAQQ LNNERSLAPF IPFRSQVGPT TVITRDGDFV RTWRIAGLAF ETQDKEELLI
RKDQLNTLFR AIASNNVALW SHNVRRRTWD HLKSFFSNPF CDALDKKYYG SFSGYRMMSN
ELYLTVIYRP VPAKISRLFN VAVHRSHAEI LQEQQLAIRK LDEIGNQIET SLRRYGGDDG
RGIEVLSTYE DKHGALCSQQ LEFYNFLLSG EWQKVRVPSC PLDEYLGTGW VYAGTETIEI
RTANATRYAR GIDFKDYASH TEPGILNGLM YSDYEYVITQ SFSFMTKRDG KEFLTRQKQR
LQNTEDGSAS QIMEMDIAID QLGRGDFVMG EYHYSLLVFA EDMETVRHNT SHAMNILQDN
GFLATVIATA TDAAFYAQLP CNWRYRPRVA GLTSLNFAGL SCFHNFRAGK RDGNPWGQAL
TLLKTPSGQP AYLNFHYSKG DEDNFDKKLL GNTRIIGQSG AGKTVLMNFC LAQAQKYLHN
APMGMCNVFF DKDQGAKGTI LAIGGKYLAI RNGEPTGFNP FQMEPTAGNI LFLEKLVQVL
VSRDGQHVTT TDESRISHAI RTVMRMRPEL RRLSTVLQNV TEGSDRQDRE NSVAKRLAKW
CFDDGTGKRG TFWWVLDCPQ DQIDFNTHSN YGFDGTDFLD NADVRTPISM YLLHRMELAI
DGRRFIYWMD EAWKWVDDEA FSEFANNKQL TIRKQNGLGV FATQMPSSLL NSKVASALVQ
QVATEIYLPN PKADYHEYTD GFKVTNEEFD IIRSMSEESR MFLVKQGHHS MICRLELNGF
DDELAILSGS SDNNELLDQV IAEVGDDPSV WLPVFQEHRK ARIASSKSTG R
//
