ID   A9X930_LUCCU            Unreviewed;       538 AA.
AC   A9X930;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=CYP12A7 {ECO:0000313|EMBL:ABK91493.1};
GN   Name=cyp12a7 {ECO:0000313|EMBL:ABK91493.1};
OS   Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Calliphoridae; Luciliinae; Lucilia.
OX   NCBI_TaxID=7375 {ECO:0000313|EMBL:ABK91493.1};
RN   [1] {ECO:0000313|EMBL:ABK91493.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Tara {ECO:0000313|EMBL:ABK91493.1};
RA   Chen Z., Batterham P.;
RT   "P450 genes and insecticide resistance in Australian blowfly Lucilia
RT   cuprina.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; DQ917669; ABK91493.1; -; Genomic_DNA.
DR   AlphaFoldDB; A9X930; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11054; CYP24A1-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24279; -; 1.
DR   PANTHER; PTHR24279:SF117; -; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW   ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
SQ   SEQUENCE   538 AA;  61944 MW;  1F188AAFA1BE86D2 CRC64;
     MFKLQNFKLL LIKQQKQQLV AFQKIRLQST ATAETLSNKE WENAKPFEEI PSISTFSFIK
     KFLPGGSYAK LDFAQLMLAF KEDFGSVARL PGFFGRPEFV ITHNVEDFEK VLRNEGIWPE
     RAGSEALQYH RHVHRAEFFQ GVEGLISTQG KSWGTFRSAV NPVMMQPKNV RLYLHKMSQV
     NKEFIERIRQ IRDQQTLEVP DNFEEEMNRF TLESISVVAL DKQLGLITEK RDNPQAMELF
     SALNGFFMYS VDVEFKPSIW KYYKTPTFMK LMKSLDTIVD VTSSYVNEAI ERLEQERKNG
     VPEKPDNEKS VLEKLIKLDK KIATVMAMDM LMAGVDTTTS SFAALMLCLA KNPEQQEKLR
     QEVLKILPQK DSEFNENSLK NIPYLRACIK ESQRIYPLTV GNARAPVKDV VISGYRVPKG
     THVSMCSLSL MRDAKHYARP NEFLPERWLR SNTEDESATK CPNASLKPTS PFLHLPFGFG
     SRSCIGRRIV EMELELVTAR LVRNYQLEFN YPTDNAFKSL AISVPNIPLK FKFTDVNY
//