ID A9YH03_DROSI Unreviewed; 242 AA.
AC A9YH03;
DT 05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Multiple edematous wings {ECO:0000313|EMBL:ABW91989.1};
DE Flags: Fragment;
OS Drosophila simulans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7240 {ECO:0000313|EMBL:ABW91989.1};
RN [1] {ECO:0000313|EMBL:ABW91989.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MD63 {ECO:0000313|EMBL:ABW91989.1};
RX PubMed=17989248; DOI=10.1101/gr.6691007;
RA Andolfatto P.;
RT "Hitchhiking effects of recurrent beneficial amino acid substitutions in
RT the Drosophila melanogaster genome.";
RL Genome Res. 17:1755-1762(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; EU217032; ABW91989.1; -; Genomic_DNA.
DR AlphaFoldDB; A9YH03; -.
DR EnsemblMetazoa; FBtr0354533; FBpp0318908; FBgn0187547.
DR Bgee; FBgn0187547; Expressed in embryo and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0007157; P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; IEA:UniProt.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF122; INTEGRIN ALPHA-PS1; 1.
DR Pfam; PF01839; FG-GAP; 1.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR SMART; SM00191; Int_alpha; 2.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS51470; FG_GAP; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 1..40
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 50..112
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 97..242
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABW91989.1"
FT NON_TER 242
FT /evidence="ECO:0000313|EMBL:ABW91989.1"
SQ SEQUENCE 242 AA; 26607 MW; 910DBC69F2BCFE78 CRC64;
ALANIGDLNK DNCEDLAVGA PYEGNGVVYI YLGSSQGLNS KPAQKILASE LGGTVPNGQP
IRTFGISISG NTDLDDNSYP DVVIGAFNSS AAVILLARPI ISIQTSVQRD ELRNMDPNTP
GCLADPSSNL TCFTFRACCS IEPYDEKNKE LRLAYSVEAE TFDHLKKFSR VFFFDRDNKR
TNVLSRVVRV HTNGRMECQA VTGYIKANTR DIQTPVRFRL KYSLVEPPLA DSALVRLNPI
LD
//
