ID AAEA_YERPY Reviewed; 311 AA.
AC B1JKI2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeA {ECO:0000255|HAMAP-Rule:MF_01544};
DE Short=pHBA efflux pump protein A {ECO:0000255|HAMAP-Rule:MF_01544};
GN Name=aaeA {ECO:0000255|HAMAP-Rule:MF_01544}; OrderedLocusNames=YPK_0484;
OS Yersinia pseudotuberculosis serotype O:3 (strain YPIII).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=502800;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YPIII;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C.,
RA Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Challacombe J.F., Green L., Lindler L.E., Nikolich M.P., Richardson P.;
RT "Complete sequence of Yersinia pseudotuberculosis YPIII.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms an efflux pump with AaeB. {ECO:0000255|HAMAP-
CC Rule:MF_01544}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01544}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01544}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000255|HAMAP-Rule:MF_01544}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000950; ACA66787.1; -; Genomic_DNA.
DR RefSeq; WP_012303486.1; NZ_CP009792.1.
DR AlphaFoldDB; B1JKI2; -.
DR SMR; B1JKI2; -.
DR KEGG; ypy:YPK_0484; -.
DR PATRIC; fig|502800.11.peg.1094; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR HAMAP; MF_01544; AaeA; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR022871; PHBA_efflux_pump_AaeA.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF12; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..311
FT /note="p-hydroxybenzoic acid efflux pump subunit AaeA"
FT /id="PRO_1000185278"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01544"
SQ SEQUENCE 311 AA; 34343 MW; 8735684261C3DE8B CRC64;
MSTFSLKIIR VGITVLVVVL AVIAIFNVWA FYTESPWTRD AKFTADVVAI APDVSGLLTE
VPVKDNQLVQ KGQILFVIDQ PRYQQALAEA EADVAYYQTL AAEKQRESSR RHRLGIQALS
QEEIDQASNV LQTVQHQLAK AIAVRDLARL DLERTTVRAP AEGWVTNLNV HAGEFINRGA
TAVALVKKDT FYILAYLEET KLEGVKPGYR AEITPLGSNR ILHGTVDSIS AGVTNSSSSA
DSKGLATIDN NLEWVRLAQR VPVKIHLDSE DQQYLYPAGT TATVVITGPN DRDPHQVSPM
TKLMHRLREF G
//
