ID ADCE_DICDI Reviewed; 564 AA.
AC Q55GN8;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=Arrestin domain-containing protein E;
GN Name=adcE; ORFNames=DDB_G0267584;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000003; EAL73245.1; -; Genomic_DNA.
DR RefSeq; XP_647146.1; XM_642054.1.
DR AlphaFoldDB; Q55GN8; -.
DR SMR; Q55GN8; -.
DR STRING; 44689.Q55GN8; -.
DR PaxDb; 44689-DDB0267093; -.
DR EnsemblProtists; EAL73245; EAL73245; DDB_G0267584.
DR GeneID; 8615949; -.
DR KEGG; ddi:DDB_G0267584; -.
DR dictyBase; DDB_G0267584; adcE.
DR eggNOG; ENOG502SBW6; Eukaryota.
DR HOGENOM; CLU_483515_0_0_1; -.
DR InParanoid; Q55GN8; -.
DR OMA; MTETRME; -.
DR PRO; PR:Q55GN8; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02656; MIT; 2.
DR Gene3D; 2.60.40.640; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF04212; MIT; 2.
DR SMART; SM01017; Arrestin_C; 1.
DR SMART; SM00132; LIM; 1.
DR SMART; SM00745; MIT; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF116846; MIT domain; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW LIM domain; Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..564
FT /note="Arrestin domain-containing protein E"
FT /id="PRO_0000363158"
FT DOMAIN 348..413
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00125"
FT REGION 74..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 63571 MW; 20324A6A973AB1DD CRC64;
MSSEILQTGL QLVKSAIDAD NQKNYSLACN LYDQAVLNLK LALVAEREPS KNALISSKIE
EYSQRNKFIK NLLSQQPQSS QPSQPQQSQF SFPSVPSSIS PSINQQQQQQ QQQINNNNNS
ILSSFPSAGN TNNNNNNTSN GFSPPNLNKN EQLSKLNSLS IGNNQSTNRQ LSRVEAYEAA
KNFSLKGRKE EEVKNYRGAS QCYEEACNYY LMAIKSEPDP TLKKNLSDEA KIYLDRIEVL
KPFAASQPQP QQPQQPQPQQ PQQQQFQQQS YNNNNSTQSM LSSFPSFNGS TNSLNNSLNN
SNNNFNQILT NSNMPIAQQN FLQNHQFNQS NNSFNNATSS LPLTFSGDKC AACDALLSTN
SIKALDRNWH AECFQVSIIC AGCQKPFALS NLSLKVKDNR AYHPMCFEST TGLSQEEIRT
FVGSSKQLFF SIQLQRKFYR AGETIQFGFT IDNGTTKKVE KVVAYLLMTE TRMEITGTAY
ERKPKRTIKK LGRCEFHHSN RFPLIKDRFE GDFFYSIPPN ILPSEVTGVD ASFVREYQLI
VKCVGPPLKI MTVKLKFNLT ILDK
//
