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Database: UniProt
Entry: APEB_BORBU
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Original site: APEB_BORBU 
ID   APEB_BORBU              Reviewed;         423 AA.
AC   O51572;
DT   24-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   07-JUN-2017, entry version 105.
DE   RecName: Full=Probable M18 family aminopeptidase 2;
DE            EC=3.4.11.-;
GN   Name=apeB; OrderedLocusNames=BB_0627;
OS   Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM
OS   4680).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / B31 / CIP 102532 / DSM 4680;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K.,
RA   Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D.,
RA   Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J.,
RA   Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D.,
RA   Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A.,
RA   Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K.,
RA   Roberts K.M., Hatch B., Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia
RT   burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the peptidase M18 family. {ECO:0000305}.
DR   EMBL; AE000783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; B70178; B70178.
DR   RefSeq; WP_023003298.1; NC_001318.1.
DR   RefSeq; YP_008686584.1; NC_001318.1.
DR   ProteinModelPortal; O51572; -.
DR   MEROPS; M18.002; -.
DR   PRIDE; O51572; -.
DR   GeneID; 1195478; -.
DR   KEGG; bbu:BB_0627; -.
DR   PATRIC; fig|224326.49.peg.1017; -.
DR   OMA; CFDHEEI; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:CAFA.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05639; M18; 1.
DR   HAMAP; MF_00467; Aminopeptidase_M18_2; 1.
DR   InterPro; IPR033818; Aminopeptidase_I.
DR   InterPro; IPR022984; M18_aminopeptidase_2.
DR   InterPro; IPR001948; Peptidase_M18.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
PE   3: Inferred from homology;
KW   Aminopeptidase; Complete proteome; Hydrolase; Metal-binding;
KW   Metalloprotease; Protease; Reference proteome; Zinc.
FT   CHAIN         1    423       Probable M18 family aminopeptidase 2.
FT                                /FTId=PRO_0000173460.
FT   METAL        84     84       Zinc. {ECO:0000255}.
FT   METAL       157    157       Zinc. {ECO:0000255}.
FT   METAL       397    397       Zinc. {ECO:0000255}.
SQ   SEQUENCE   423 AA;  47381 MW;  BE62EEF05A2B100B CRC64;
     MVXXKTLEPK FFQSLLDNSP TPYHLVNYIE EKLINYFNAQ QLKLNEKWKI KTGSYYIKKE
     GTSLIAFNID VKKKYEPFLI AAAHTDSPGL KLKIDATEKV SGVFYNHIEV YGSPIISTWI
     DRDLSLAGIV YFKKNENIES KLINIENIGI IPNLAIHLNR QINEGFKYNA HDNLTVISST
     KKAIKDNILE QLGIECENFL SCDLIFTESQ PSKIIGTEGE FLASKNLDNK SGCHAIMNSY
     VHTSNDKNKI AVFFDNEEVG SLTSRGADSN FLSEVLERID IALDLTREEH LIKTNKSFNI
     SIDSVHGIHP GYTSKHDPNY QANLGKGVVV KNSANFRYAT TSTGFAKLKN LAIKNNIKIQ
     EIIMKANVPS GTTIGPISNA RTGIETIDIG TPMWAMHSLR ETVSIADHIE AIKLLRAFFE
     KGI
//
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