ID   B0BW70_RICRO            Unreviewed;       805 AA.
AC   B0BW70;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=VirB4 ATPase {ECO:0000313|EMBL:ABY72096.1};
GN   Name=virB4.1 {ECO:0000313|EMBL:ABY72096.1};
GN   OrderedLocusNames=RrIowa_0178 {ECO:0000313|EMBL:ABY72096.1};
OS   Rickettsia rickettsii (strain Iowa).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=452659 {ECO:0000313|EMBL:ABY72096.1, ECO:0000313|Proteomes:UP000000796};
RN   [1] {ECO:0000313|EMBL:ABY72096.1, ECO:0000313|Proteomes:UP000000796}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa {ECO:0000313|EMBL:ABY72096.1,
RC   ECO:0000313|Proteomes:UP000000796};
RX   PubMed=18025092; DOI=10.1128/IAI.00952-07;
RA   Ellison D.W., Clark T.R., Sturdevant D.E., Virtaneva K., Porcella S.F.,
RA   Hackstadt T.;
RT   "Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and
RT   avirulent Rickettsia rickettsii Iowa.";
RL   Infect. Immun. 76:542-550(2008).
CC   -!- SIMILARITY: Belongs to the TrbE/VirB4 family.
CC       {ECO:0000256|ARBA:ARBA00006512}.
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DR   EMBL; CP000766; ABY72096.1; -; Genomic_DNA.
DR   RefSeq; WP_012150361.1; NC_010263.3.
DR   AlphaFoldDB; B0BW70; -.
DR   GeneID; 79936936; -.
DR   KEGG; rrj:RrIowa_0178; -.
DR   eggNOG; COG3451; Bacteria.
DR   HOGENOM; CLU_008341_3_0_5; -.
DR   Proteomes; UP000000796; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004346; CagE_TrbE_VirB.
DR   InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR043964; P-loop_TraG.
DR   NCBIfam; TIGR00929; VirB4_CagE; 1.
DR   PANTHER; PTHR30121:SF6; TYPE IV SECRETION SYSTEM PROTEIN CAGE; 1.
DR   PANTHER; PTHR30121; UNCHARACTERIZED PROTEIN YJGR-RELATED; 1.
DR   Pfam; PF03135; CagE_TrbE_VirB; 1.
DR   Pfam; PF19044; P-loop_TraG; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          450..708
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          156..183
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   805 AA;  91095 MW;  0EADA548405BBAD3 CRC64;
     MKLFRTRAAK ELRSKQERPT SHFIPYKCHW DSNTILTKDN SLLQVIKING FSFETADDED
     LEIKKNIRNA LLKNMASGNI VMYFHTIRRR KAVIFDDTEF TYDPTVKVPN DFITYLGAEW
     RKKHAGARSF FNELYVSILY KPDTGGVAIV EYFLKKLRQK SNKTAWENDM KEMKENLQEM
     STRVINTFRS YGARLLGVCQ TQSGSYCEIL EFLSSLINCG DSPGPIALPR GTIDEYLPTH
     RLFFDSRTIE ARSPLGKKYA GMISILEYGP NTSAGIFDGF LQMPFEFVMT QSFVFVNRTV
     AIGKMQLQQN RMIQAGDKAT SQIAEINTAL DMATSGDIAF GEHHLSLLCS ANNIKALEDI
     LSMAAVELSN SGIQPVREKV NMEPSYWGQL PGNMDYIVRK STINTLNMAS FASQHNYPLG
     KIRDNHWGEY VTVLDTTSGT PFYFNFHVRD VGHTLIIGPT GAGKTVLMNF LCAEAQKFKP
     RMFFFDKDRG AEIFIRALKG VYTVIDPGLK CNFNPLQLED TSENRTFILE WLRVLVTSNG
     ESLTAQDNKI LSQAVSGNFR LAKQDRRLSN VIAFLGIDTP NSLASRIAMW VGKGSHAKIF
     DNEIDDIDLQ KARVFGFDMT ELLKDPVSLA PVLLYIFHRI NISLDGQKTM IVLDEAWALI
     DNPVFAPKIK DWLKVLRKLN TFVIFATQSV EDAAKSRISD TLIQQTATQI FLPNLKATDI
     YRSAFMLSQR EYILIKTTDP TTRYFLIKQG VDAVVAKVSL DGMDNIISVL SGRIETVILL
     DQIREKHGND PDKWLPIFYA AVKTL
//