ID B0CJD7_BRUSI Unreviewed; 391 AA.
AC B0CJD7;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Cobw protein {ECO:0000313|EMBL:ABY38889.1};
GN OrderedLocusNames=BSUIS_A1876 {ECO:0000313|EMBL:ABY38889.1};
OS Brucella suis (strain ATCC 23445 / NCTC 10510).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=470137 {ECO:0000313|EMBL:ABY38889.1, ECO:0000313|Proteomes:UP000008545};
RN [1] {ECO:0000313|EMBL:ABY38889.1, ECO:0000313|Proteomes:UP000008545}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23445 / NCTC 10510 {ECO:0000313|Proteomes:UP000008545};
RA Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C.,
RA Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S.,
RA Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M.,
RA Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H.,
RA Bruce D., Detter C., Munk C., Brettin T.S.;
RT "Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000911; ABY38889.1; -; Genomic_DNA.
DR RefSeq; WP_006071735.1; NC_010169.1.
DR AlphaFoldDB; B0CJD7; -.
DR KEGG; bmt:BSUIS_A1876; -.
DR HOGENOM; CLU_017452_0_2_5; -.
DR Proteomes; UP000008545; Chromosome I.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 269..364
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 242..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 43198 MW; 0E0D36D61978C9DF CRC64;
MPDPIPVSVL TGFLGSGKTT LLNRLLKDPA LSDTAVIINE FGEVSIDHLL VEQASEGVIE
LADGCLCCTV RGELVDTLAD LIDRLQTGRI KALKRVIIET TGLADPAPVL HSIMGHPLLT
QVFRLDGVLA TVDAVNGMAT LDNHEEAVKQ AAMADRIILT KTDLPEAQAG LPALKARLRT
LNPGADILEA GEERTGYAAL FECGLYNPQT KSADVRRWLK AEAYEDEHHG HGHVCGPDCG
HDHHHHDHHH DHHNDQGYAH HHHHHDDAIR SFSLRHDAPI PVSTFEMFLD LLRSTHGEKL
LRMKGIVQIA EDPDRPVVIH GVQKIFHPPA RLPQWPQGKR ETLLVLIVKD LPEAYVRELF
DAFLGRPGLD RPDRAAMTEN PLAIPGFSPR R
//
