ID B0DWN0_LACBS Unreviewed; 1023 AA.
AC B0DWN0;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EDR01008.1};
GN ORFNames=LACBIDRAFT_191964 {ECO:0000313|EMBL:EDR01008.1};
OS Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS (Laccaria laccata var. bicolor).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=486041 {ECO:0000313|Proteomes:UP000001194};
RN [1] {ECO:0000313|EMBL:EDR01008.1, ECO:0000313|Proteomes:UP000001194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 / ATCC MYA-4686 {ECO:0000313|Proteomes:UP000001194};
RX PubMed=18322534; DOI=10.1038/nature06556;
RA Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA Tuskan G., Grigoriev I.V.;
RT "The genome of Laccaria bicolor provides insights into mycorrhizal
RT symbiosis.";
RL Nature 452:88-92(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; DS547144; EDR01008.1; -; Genomic_DNA.
DR RefSeq; XP_001888403.1; XM_001888368.1.
DR AlphaFoldDB; B0DWN0; -.
DR GeneID; 6084050; -.
DR KEGG; lbc:LACBIDRAFT_191964; -.
DR HOGENOM; CLU_002458_3_0_1; -.
DR InParanoid; B0DWN0; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000001194; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001194};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 574..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..704
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 710..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..208
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 230..419
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 430..704
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 937..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..954
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..1001
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1023 AA; 115907 MW; 9137DDBFE6DB4D72 CRC64;
MASIFIQLLE EGGGGGDGEH KLPPGSPPMQ KFEGPWFTTQ LTISLSVGLT SFFLFSYCRT
RWPLIFAPRT KLKGFSPHEA HAHQAFFGWI MPTIRTSEFT VLQIVGLDAA VLLNFFKMSF
YLFSVCSLFA TTMLMPLNWK HNKDLDDDTD WPDDKDDWPI LRKRAFDPVT NHTGHDWLDL
ISDANSYLSL HLMFTYLFTL LALYFIYKNY RRFLRSRQLF SLELVHSIPA RTVIVTDLPN
HLQGERPLAD YFENMGLAVE SVTVCREVGS LKTLLDRRTR ALLELETAWV SYVGNPSTVE
EYDPEDNGIP LLVDTDVEGG QQSGQGRLVV PHRKRPTLRP GWFKPKVDAL EYLENQFKEA
DELVKKRRRT GKFKATRAAF VTFEKMSSAQ IAVQVAHAPG PGQITTYPAP EPRDIVWSNM
APSQATIRTR DFFVLAIMGF LLFFWIFPIT ALASLLSYKE IKKSMPWLGN LIDSNEQVRA
IVQNSLPSVA MISLNALLPF ILEALTYVQG YRARSWVEYS LLKKYFLFLL VNVVFIFLLA
STYWQLVRDL ANSPAKVPEK LAQALQAGRA RHFFLSYVIL QGLGIMPLQL LNLGVIVPRF
FYRMFLTRTP RDFAELNAPP MINYGVVYPQ AILMFVITML YSVVQPLIVI FGAIYFGVAY
VVYKYKLLFV FYKPYESQGQ AWPITFIRLI WGVVIFLLFM IGIFTLRKSY ILSSLLVPLL
IGTVVWSWYV DKELKPLSKF VSLSSVFEVQ RGEETADVLR LRAGHPVTWS QSNLNRRRYA
QNDDTLYVAP EDERTDYSQP PMANWYSGVL NTGKRRYGHP ALNGVLPEPW LPLKKGQTLI
NNDRGANARA HKDPNQAVVL TLRKRYSVSA RRASRVPAAG GETIALGGPS STNQLDPTVV
SNPWEDAAGN TRQRSHTLSH RLSYDHASGV IMLPDDGGDW IEADDDDSDE VDYGTENGGL
ERSLTESMLS SPGEEGNGGQ QLRQPALSSS PTTSTPSRPS RYGTYFHHPE RRRLQIPGAF
PRS
//
