ID B0ECX2_ENTDS Unreviewed; 1326 AA.
AC B0ECX2;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN ORFNames=EDI_278350 {ECO:0000313|EMBL:EDR27664.1};
OS Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370354 {ECO:0000313|Proteomes:UP000008076};
RN [1] {ECO:0000313|Proteomes:UP000008076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PRA-260 / SAW760 {ECO:0000313|Proteomes:UP000008076};
RA Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT "Annotation of Entamoeba dispar SAW760.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS548795; EDR27664.1; -; Genomic_DNA.
DR RefSeq; XP_001736147.1; XM_001736095.1.
DR EnsemblProtists; EDR27664; EDR27664; EDI_278350.
DR GeneID; 5881128; -.
DR KEGG; edi:EDI_278350; -.
DR VEuPathDB; AmoebaDB:EDI_278350; -.
DR eggNOG; ENOG502RFSU; Eukaryota.
DR OMA; AFRQHTF; -.
DR OrthoDB; 23913at2759; -.
DR Proteomes; UP000008076; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR17616:SF8; YES-ASSOCIATED PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 5..38
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 50..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1326 AA; 149908 MW; 60B0CC2FA5FA7657 CRC64;
MYSSYQLPPG WRIAYTTDGK VYYLDDKNKT THWHLPQNLY QQQINSQPNN LNKQFTYSNK
SPNAPKRSPG SIQSTFVEFK KPPPFIISTT PKLTSNSLLT SSGTISNDLK DTFEIIDDFF
QPSKKPNTPT IKKDNEVVLS SDKKIKPNIN LSTLIEDKVN LRVPLPYTQI NKSFNYPIPR
PAINTNICPC GKEFGYLKHQ KQQCKCCRRY FGNDCLTNQK CILCNYHQDG KCLGSLLTYC
ESSDYKDANI GLQTLFTANS INTFPTKVII ESGMIPAILT ALKHPFCCLS VLNLIVAFRQ
HTFIRFTDKE LSHFGRLGST SDDGRIIELC IYLLLAAVIE KLPLPSTLFE LISLPRSISQ
QLYQSHILRL ALSQYHFHPE ITMALISSMK KQNIVLSSVM IYDLIQLLPN SIILDILTFS
SFNPTQRLAL LNSNILSSLI PTAESLQITI NLIDTQYIPF FEGHMELIAH LLIDEHALTG
ELSKKCCLFL SSPQKQEFIT SLIQIGAVPL LLRSVITEKI GIGLNIVAEA KMKECINILL
SISENNEVRE QWLGAMKALG GINKDMTDYI LIVVNCIKQQ ESVKSALELM LISESIIEMI
KQTDENLIGL LQTEYRGGAA KVILKVFQMG EKQLLINKGL FSAIAQSIES ECNEEVLKLI
PLFIGETQSG ILLQRIIHKI AGTYLLQTQF TQISLETLVL LCKDQTILPL LHSVQINGFE
NFMQFLVLRI FTAKPEIKIC YLQLFHNYII TSYCDEIKKY SIANIVCQIY FNSDDHLILI
ECIKCLNKLI SLPQTCGSIL YRQIEQKLIS LLFSVYSLSN SNQILLFEEC IKLVLTLSTL
HPSHLPILLP IIQLIPFDRI PNSTKSNCLL LLLQLTSIDP SVSALIYPAL SNLTYASTQI
LAKLISISTT ITPLYKLYYY FTEEVLIDFL KTGDIDLVTR ALEIISTRSP SVPLVCSLFK
LLTTSLPEET KLSTFHILQQ ILPDITIINL LPSLNKILPL LIKLHGTDLL PLFSIVMTAC
PKEFSSMIIK TNLKDCLVQS KNLQQFISLA LTLDPIDLLP YFLPLLNSLI TSNPIFVKTV
LAALTTLLNK SESVIDNEGL VVSLAELLSN KQLIEQSVSH FKIILKHQCF VREYLKNGID
NLIQFYKNNQ LKEEIIEAVK QNCCEESLPL LNYILEDAIQ GNKNALNAVN QFMKKGIGRE
CVTLKNKELL ALSINCPNAL CSLSLINDTQ LESTLLLQLI DRREQLTNKQ LVYLIRIIAQ
QMLFGFDIES SLVSKLLENN DEEVIIELMS LIVLNPFKYS VCLKDFPLSN YHSLEPFVTY
LQPFII
//
