ID B0EI18_ENTDS Unreviewed; 239 AA.
AC B0EI18;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=EDI_293790 {ECO:0000313|EMBL:EDR25833.1};
OS Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370354 {ECO:0000313|Proteomes:UP000008076};
RN [1] {ECO:0000313|Proteomes:UP000008076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PRA-260 / SAW760 {ECO:0000313|Proteomes:UP000008076};
RA Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT "Annotation of Entamoeba dispar SAW760.";
RL Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Rho GTPase-activating protein involved in the signal
CC transduction pathway. {ECO:0000256|ARBA:ARBA00037092}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS549371; EDR25833.1; -; Genomic_DNA.
DR RefSeq; XP_001737870.1; XM_001737818.1.
DR AlphaFoldDB; B0EI18; -.
DR EnsemblProtists; EDR25833; EDR25833; EDI_293790.
DR GeneID; 5882922; -.
DR KEGG; edi:EDI_293790; -.
DR VEuPathDB; AmoebaDB:EDI_293790; -.
DR eggNOG; KOG4724; Eukaryota.
DR OMA; HIDENST; -.
DR OrthoDB; 4177at2759; -.
DR Proteomes; UP000008076; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
FT DOMAIN 10..199
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 239 AA; 27547 MW; 5747E79176DB848B CRC64;
MKQNEKVIGR RLKEVPTINK LPYPIYDMLE KLSSKWEYIL TEGIFRVPGN MTDIIAIKKR
YENGESVNFT NVQISTVASL LKNYLKEIPG ALVDNENKDL FNVTISMFEM DNSLKDLVTK
NIKDALSFLP LLNYITLKHI IFHLHLIAQY SQFNLMDSNN LATVFAPVLF SLSIEELMNN
KNYAIVTIKF LIDNYNDVFT INNKLMDGSY LEPCDYQVPF GKCPKELLHL SDNNPQSIH
//
