ID   B0ERW5_ENTDS            Unreviewed;       529 AA.
AC   B0ERW5;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Vacuolar protein sorting-associated protein, putative {ECO:0000313|EMBL:EDR22760.1};
GN   ORFNames=EDI_336600 {ECO:0000313|EMBL:EDR22760.1};
OS   Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370354 {ECO:0000313|Proteomes:UP000008076};
RN   [1] {ECO:0000313|Proteomes:UP000008076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PRA-260 / SAW760 {ECO:0000313|Proteomes:UP000008076};
RA   Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT   "Annotation of Entamoeba dispar SAW760.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; DS550549; EDR22760.1; -; Genomic_DNA.
DR   RefSeq; XP_001740837.1; XM_001740785.1.
DR   AlphaFoldDB; B0ERW5; -.
DR   EnsemblProtists; EDR22760; EDR22760; EDI_336600.
DR   GeneID; 5886011; -.
DR   KEGG; edi:EDI_336600; -.
DR   VEuPathDB; AmoebaDB:EDI_336600; -.
DR   eggNOG; KOG1299; Eukaryota.
DR   OMA; VQVTRHC; -.
DR   OrthoDB; 49088at2759; -.
DR   Proteomes; UP000008076; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF3; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}.
SQ   SEQUENCE   529 AA;  60362 MW;  D7A1730A014C8099 CRC64;
     MDVISSLQEY LNFTFNETPG MKALIMDSDT IPVVSILFGM TEIIQKEVYL VQQLSDQTRD
     TLPHLNAICL LRPTKENMEL LRKELNNPKY GKYYLFFTNF LDSTQISLLS QSDVHEVVQK
     VMELYVDYMP VNDDLFISSC PNYYSVVGSN SMKNEQKTID SLMALCLSLK KNPAIRYQQN
     SELSKRIAEG LTQGLERQKK IFGPMNGTTI LILDRSFDPI TPLLTQWTYQ AMIHEFIGIE
     NGKIVLDNKP IILSNDSFFN EHMYLLFSDI TDSIIASVNE LTKKAGIASK QYRSLEEMKE
     TIEQIPQLKK ESAGVKKHLG IMNVINKIVS RRKMLDVSRL EQDIVCGSGR QELYQSVIQF
     FEGDYEVEDK LRVGLLYALK YEDKAQDIIE ELTIKGIPRN QIQLIDVVLR YAGSSKRPIE
     IFNKVKSIVG FVKKSVAGVE NVFVQHKPVL EQLYDPLINQ QLLDKFPFCR GSSANGREFI
     IYIVGGVTLE EEVSIATRNR TNPTQKFIIG GSDLLNSSKF IELLESMKK
//