ID B0KC54_THEP3 Unreviewed; 519 AA.
AC B0KC54;
DT 18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT 18-MAR-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN OrderedLocusNames=Teth39_1771 {ECO:0000313|EMBL:ABY95408.1};
OS Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) (Clostridium
OS thermohydrosulfuricum).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=340099 {ECO:0000313|EMBL:ABY95408.1, ECO:0000313|Proteomes:UP000002156};
RN [1] {ECO:0000313|Proteomes:UP000002156}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33223 / DSM 2355 / 39E
RC {ECO:0000313|Proteomes:UP000002156};
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Bruce D., Goodwin L., Saunders E., Brettin T.,
RA Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Hemme C., Fields M.W., He Z., Zhou J.,
RA Richardson P.;
RT "Complete sequence of Thermoanaerobacter pseudethanolicus 39E.";
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP000924; ABY95408.1; -; Genomic_DNA.
DR RefSeq; WP_012269592.1; NC_010321.1.
DR AlphaFoldDB; B0KC54; -.
DR STRING; 340099.Teth39_1771; -.
DR KEGG; tpd:Teth39_1771; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_2_9; -.
DR Proteomes; UP000002156; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 3.30.70.2120; -; 1.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ABY95408.1};
KW Cilium {ECO:0000313|EMBL:ABY95408.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:ABY95408.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002156};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 22..119
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 244..505
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 519 AA; 56961 MW; D4EEBC2F324EADD4 CRC64;
MDPISMNSYN MSNLLRISGL ATGLDTDSIV QQLIRAASIP LDRLEQQKQW YQWQQEDLRD
INSQLMSLRN DNVFKLKLQG TFMAKTVTSS NPSVATATAG ANAVNGSYTI SVSQLAQAAT
TASTDKIGAA TKNSDGTYTY NALNNTGSDI TLYLKGLDGN DKEIIIKNGA TIKDVVAAIN
AKTNETGVSA TYDPGLDRLF LVSNFTGTNS KIDFSGTTDP TAQNFLTTTL KLDSKVLDTG
GITGQDALFT FNGVQMTSST NNVTVAGINI TLTGTSNSTT TLTVLTDVDK IYNTIKSFVD
SYNDIITKIN AKLTEKRYYD YPPLTSEQKQ AMKDSDIKLW EEKARSGNLN NDETLMRVYY
SMRNVVSSTV SGVGSLSSIG ITTGQWYEGG KLYIDETKLK DAIANDLDKV MKIFAGVYET
DSNGNTTLKT SGIAQNLYDT LKQGIDAITR KAGSTAQLYD TSFIGNRIRE IDDRIAQMQR
YLNDLEKRYY AQFTQLEMYV GQMNSQSAWL SQQIGVMMK
//
