ID   B0MJX3_9FIRM            Unreviewed;       446 AA.
AC   B0MJX3;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Orn/Lys/Arg decarboxylase, major domain protein {ECO:0000313|EMBL:EDS02004.1};
GN   ORFNames=EUBSIR_00106 {ECO:0000313|EMBL:EDS02004.1};
OS   [Eubacterium] siraeum DSM 15702.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=428128 {ECO:0000313|EMBL:EDS02004.1, ECO:0000313|Proteomes:UP000005326};
RN   [1] {ECO:0000313|EMBL:EDS02004.1, ECO:0000313|Proteomes:UP000005326}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15702 {ECO:0000313|EMBL:EDS02004.1,
RC   ECO:0000313|Proteomes:UP000005326};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDS02004.1, ECO:0000313|Proteomes:UP000005326}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15702 {ECO:0000313|EMBL:EDS02004.1,
RC   ECO:0000313|Proteomes:UP000005326};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Eubacterium siraeum (DSM 15702).";
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC       {ECO:0000256|ARBA:ARBA00010671}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDS02004.1}.
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DR   EMBL; ABCA03000021; EDS02004.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0MJX3; -.
DR   Proteomes; UP000005326; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.90.100.10; Orn/Lys/Arg decarboxylase, C-terminal domain; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR   InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43277:SF4; ARGININE DECARBOXYLASE; 1.
DR   Pfam; PF01276; OKR_DC_1; 1.
DR   Pfam; PF03711; OKR_DC_1_C; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          60..267
FT                   /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT                   attachment site"
FT                   /evidence="ECO:0000259|Pfam:PF01276"
FT   DOMAIN          395..430
FT                   /note="Orn/Lys/Arg decarboxylase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03711"
SQ   SEQUENCE   446 AA;  48275 MW;  F388E48937C80780 CRC64;
     MDISNLIEEM TTPIHDFLVK NSESHTIRCY MPGHKGTEDP LDITEIDGAD SLYDTDTNGG
     KGIIAQSEKN ASKLFGSKRT LYSCSGSTLA IQTMLTLAKL RGNGKDHVIA GRYSHRSFIN
     SCVLLGLIPS WVYPEEYLCA AVTPESIEAK INSRTLAVFI NSIDYYGGMS NISAIAEVCH
     SHGIPLLVDN AHGAYLKFAP VDLHPMTLGA DMCADSAHKT LPVLTGGAYL HIANEKYCAM
     AKEAMALTAT SSPSYLILDS LDRCNRTIAE KPFHIAEICN KVTALKRHCA DMGYVLSQSD
     YMKVTFDCAA VHSTGFAMAE MLKEFGIECE YADEYRCVLL FGSGSTDVDF ETIKTVLRAN
     TPRSVFVRDL PSPPVHIRTQ TACSPAKAYF SGKVRLPVMM TVGKVCAGAV APCPPGIPLI
     MPGEVVTIDA ARALRDKGIA DIPIVV
//