ID B0MQV7_9FIRM Unreviewed; 352 AA.
AC B0MQV7;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Bacterial peptidase A24, N-terminal domain protein {ECO:0000313|EMBL:EDR99874.1};
GN ORFNames=EUBSIR_02224 {ECO:0000313|EMBL:EDR99874.1};
OS [Eubacterium] siraeum DSM 15702.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillospiraceae incertae sedis.
OX NCBI_TaxID=428128 {ECO:0000313|EMBL:EDR99874.1, ECO:0000313|Proteomes:UP000005326};
RN [1] {ECO:0000313|EMBL:EDR99874.1, ECO:0000313|Proteomes:UP000005326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15702 {ECO:0000313|EMBL:EDR99874.1,
RC ECO:0000313|Proteomes:UP000005326};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDR99874.1, ECO:0000313|Proteomes:UP000005326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15702 {ECO:0000313|EMBL:EDR99874.1,
RC ECO:0000313|Proteomes:UP000005326};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Eubacterium siraeum (DSM 15702).";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase A24 family.
CC {ECO:0000256|ARBA:ARBA00005801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDR99874.1}.
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DR EMBL; ABCA03000053; EDR99874.1; -; Genomic_DNA.
DR AlphaFoldDB; B0MQV7; -.
DR Proteomes; UP000005326; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR Gene3D; 1.20.120.1220; -; 1.
DR InterPro; IPR000045; Prepilin_IV_endopep_pep.
DR InterPro; IPR010627; Prepilin_pept_A24_N.
DR PANTHER; PTHR30487:SF0; PREPILIN LEADER PEPTIDASE_N-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR30487; TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME; 1.
DR Pfam; PF06750; A24_N_bact; 1.
DR Pfam; PF01478; Peptidase_A24; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..104
FT /note="Prepilin peptidase A24 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06750"
FT DOMAIN 114..215
FT /note="Prepilin type IV endopeptidase peptidase"
FT /evidence="ECO:0000259|Pfam:PF01478"
SQ SEQUENCE 352 AA; 38545 MW; 248E28FFE0A6435D CRC64;
MVIYMTGILW YDTVICVLVF IFGSVIGSFL NVVIYRTPLH MSIVNGPSHC FSCGERIKPY
DLVPIFSWIF LGGKCRKCKA PISARYTVVE ALTGIMFLLA YIRFSASLPM VVAIVFFSLL
IVLSCIDIDH MEIPYWCTIS IAVLGIATFF TEPNMPWWEH FAGAAVIAVP FAILALFGGM
GGGDVQLMAA SGFVLGWKIV PSAVIGVVVG AVYGLIVLCV SSRFTKEQSA KISEKLTDWC
EGKAVDNSKD VIIGEFEHGK CKIDPELFEE KAWNISGDEL KAATESLSSE LNEAMGELPD
SKEYVFRANV ENGKITKIKL RRRIAFGPAL SVGLAVGMLC GETIIKAYLS ML
//
