ID B0NSK2_BACSE Unreviewed; 391 AA.
AC B0NSK2;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EDS14778.1};
GN ORFNames=BACSTE_02466 {ECO:0000313|EMBL:EDS14778.1};
OS Bacteroides stercoris ATCC 43183.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=449673 {ECO:0000313|EMBL:EDS14778.1, ECO:0000313|Proteomes:UP000004713};
RN [1] {ECO:0000313|EMBL:EDS14778.1, ECO:0000313|Proteomes:UP000004713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43183 {ECO:0000313|EMBL:EDS14778.1,
RC ECO:0000313|Proteomes:UP000004713};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Bacteroides stercoris(ATCC 43183).";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDS14778.1, ECO:0000313|Proteomes:UP000004713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43183 {ECO:0000313|EMBL:EDS14778.1,
RC ECO:0000313|Proteomes:UP000004713};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDS14778.1}.
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DR EMBL; ABFZ02000020; EDS14778.1; -; Genomic_DNA.
DR RefSeq; WP_005655919.1; NZ_DS499674.1.
DR AlphaFoldDB; B0NSK2; -.
DR GeneID; 31797741; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_1_10; -.
DR Proteomes; UP000004713; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..391
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002753645"
FT DOMAIN 56..280
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 134..161
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 391 AA; 42323 MW; 919FE9E339F026C3 CRC64;
MKSRLVLLAC CLALLSSCGQ GDKSTGKAPE FAVITVETTT ANLTNSYPAT IKGKQDVEIR
PMVSGFITKL HVDEGSVVHK GQVLFSIDPV QYQAAVNSAK AAVETAKAAV NTQELTVSNK
RTLNQKNIIS DYDLQMAENQ LAQTKAQLAQ AEAQLINAQN NLSYTSVTSP SDGIVGTIPY
RVGSLVSPSM ATPLTTVADI SEMFAYFSMT ERQLLSLIRE GGSTKDILAK MPQVQLQLID
GTMYADSGRV ETISGVIDQT TGAVNMRALF PNKHNILRSG GTGNVVFPNP MENVIMIPQS
ATTEIQDKKF VFVAQPDNTL KNTEIQVFSL NDGKYFYVTD GLKAGDKIVI EGVQNLKDGQ
SITPITPEEK EAEYQKALKD QKEGNIQTAF N
//
