ID B0RN66_XANCB Unreviewed; 504 AA.
AC B0RN66;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:CAP49901.1};
DE EC=3.1.2.1 {ECO:0000313|EMBL:CAP49901.1};
GN Name=ach {ECO:0000313|EMBL:CAP49901.1};
GN ORFNames=XCCB100_0566 {ECO:0000313|EMBL:CAP49901.1};
OS Xanthomonas campestris pv. campestris (strain B100).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=509169 {ECO:0000313|EMBL:CAP49901.1, ECO:0000313|Proteomes:UP000001188};
RN [1] {ECO:0000313|EMBL:CAP49901.1, ECO:0000313|Proteomes:UP000001188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B100 {ECO:0000313|EMBL:CAP49901.1,
RC ECO:0000313|Proteomes:UP000001188};
RX PubMed=18304669; DOI=10.1016/j.jbiotec.2007.12.013;
RA Vorholter F.J., Schneiker S., Goesmann A., Krause L., Bekel T., Kaiser O.,
RA Linke B., Patschkowski T., Ruckert C., Schmid J., Sidhu V.K., Sieber V.,
RA Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K., Puhler A.;
RT "The genome of Xanthomonas campestris pv. campestris B100 and its use for
RT the reconstruction of metabolic pathways involved in xanthan
RT biosynthesis.";
RL J. Biotechnol. 134:33-45(2008).
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; AM920689; CAP49901.1; -; Genomic_DNA.
DR AlphaFoldDB; B0RN66; -.
DR SMR; B0RN66; -.
DR KEGG; xca:xcc-b100_0566; -.
DR HOGENOM; CLU_019748_3_0_6; -.
DR Proteomes; UP000001188; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CAP49901.1}.
FT DOMAIN 13..221
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 323..469
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 294
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 364
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 384
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 388
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 408
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 504 AA; 55008 MW; 5F7F765A595983F4 CRC64;
MSDERILNAP LRDHLVSAEA AAALIQPGET VAMSGFTGSG YPKAVPMALA QRIEAAHLQG
EAFQIKLMTG ASTAPELDGA LAKADGIAMR MPFQSDPDAR QRINAGTLDY IDIHLSHVAQ
HVWFGFYGQI DTAVVEVSAI RADGSLVPST SIGNNKTWLD LARKVIIEVN DWQPAGLDGM
HDVYYGTALP PHRKPIPLLH GDDRIGEPSL RCDPDKIVAV VRTHGPDRNS PFAAADDSSE
RIAEHLIAFL RHEVSKGRLP ANLLPLQSGV GNIPNAVLAG LARSGFRDLE AFTEVIQDGM
LALLRDGVLR YASCTGFALS PEGNEEFKRN IDFYRQRIVM RTQEISNHPE LVRRLGCIGM
NGMIEADLYG NVNSTHVMGS RIMNGIGGSG DFARNGFLSI FLSPSIAKAG SISSIVPMVS
HVDHTEHDVS VIVTEQGLAD LRGLTPKQRA RQLLEHCVHP RYRDALEDYV ARANRDSYGK
HTPHLLTEAL AWHQRWLETG DMLG
//
