ID B0TAP6_HELMI Unreviewed; 452 AA.
AC B0TAP6;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE {ECO:0000256|ARBA:ARBA00013280};
GN Name=nifE {ECO:0000313|EMBL:ABZ83698.1};
GN ORFNames=HM1_0863 {ECO:0000313|EMBL:ABZ83698.1};
OS Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliomicrobium.
OX NCBI_TaxID=498761 {ECO:0000313|EMBL:ABZ83698.1, ECO:0000313|Proteomes:UP000008550};
RN [1] {ECO:0000313|EMBL:ABZ83698.1, ECO:0000313|Proteomes:UP000008550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51547 / Ice1 {ECO:0000313|Proteomes:UP000008550};
RX PubMed=18441057; DOI=10.1128/JB.00299-08;
RA Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT of the Firmicutes containing the simplest photosynthetic apparatus.";
RL J. Bacteriol. 190:4687-4696(2008).
CC -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC prosthetic group of nitrogenase (FeMo cofactor).
CC {ECO:0000256|ARBA:ARBA00003171}.
CC -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005155}.
CC -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family.
CC {ECO:0000256|ARBA:ARBA00011002, ECO:0000256|RuleBase:RU004021}.
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DR EMBL; CP000930; ABZ83698.1; -; Genomic_DNA.
DR RefSeq; WP_012282221.1; NC_010337.2.
DR AlphaFoldDB; B0TAP6; -.
DR STRING; 498761.HM1_0863; -.
DR KEGG; hmo:HM1_0863; -.
DR eggNOG; COG2710; Bacteria.
DR HOGENOM; CLU_025876_1_1_9; -.
DR OrthoDB; 9767044at2; -.
DR UniPathway; UPA00782; -.
DR Proteomes; UP000008550; Chromosome.
DR GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR Gene3D; 3.40.50.12380; Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal; 1.
DR Gene3D; 3.40.50.1980; Nitrogenase molybdenum iron protein domain; 1.
DR InterPro; IPR000510; Nase/OxRdtase_comp1.
DR InterPro; IPR000318; Nase_comp1_CS.
DR InterPro; IPR005973; NifE.
DR NCBIfam; TIGR01283; nifE; 1.
DR PANTHER; PTHR42956; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR PANTHER; PTHR42956:SF1; NITROGENASE IRON-MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN NIFE; 1.
DR Pfam; PF00148; Oxidored_nitro; 1.
DR SUPFAM; SSF53807; Helical backbone' metal receptor; 1.
DR PROSITE; PS00699; NITROGENASE_1_1; 1.
PE 3: Inferred from homology;
KW Nitrogen fixation {ECO:0000256|ARBA:ARBA00023231,
KW ECO:0000256|RuleBase:RU004021};
KW Reference proteome {ECO:0000313|Proteomes:UP000008550}.
FT DOMAIN 38..433
FT /note="Nitrogenase/oxidoreductase component 1"
FT /evidence="ECO:0000259|Pfam:PF00148"
SQ SEQUENCE 452 AA; 48978 MW; 2093B0DABC50DB5B CRC64;
MFVNLSKLNL REECPLSDKG APKLCLKALP GEGAERSCAF DGARVVLMPI TDAAHVVHGP
IACAGNSWDN RGARSSGAQL YRRGLTTDLM EMDVVYGGEK KLIQAIVEVA AKHRPKAVFV
YATCLSALIG DDLEFACRQA QAQVPVPVIP VNAPGFLGDK NIGNRVSGEV LFQQVIGTAE
PEGSHPFAIN FIGEYNIAGD LWGVLPSLEA IGVKLQSCIS GDARFDDLRT AHRAKLNILV
CSKSLTNLVK QMEKKYGIPY IEGSFYGIHD TSKTLRAIAE AFGDADLIAR TEDHIRQKEA
ETRALIAPYR QGLEGKRAVL FTGGVKTWSM VTTLKELGIE VLAGGTQNST PEDFLRMKAL
MDPEAHIIED TSAAGFLTLI KEKAPDLIVA GGKTKYLAHK TRTPFLDINH GRNLPYAGYN
GMITFAKAVA RTVFSPVWEK MQKPFPAGGD VP
//
