ID B0TC29_HELMI Unreviewed; 511 AA.
AC B0TC29;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=phosphoenolpyruvate carboxykinase (ATP) {ECO:0000256|ARBA:ARBA00012363};
DE EC=4.1.1.49 {ECO:0000256|ARBA:ARBA00012363};
GN Name=pckA {ECO:0000313|EMBL:ABZ85302.1};
GN ORFNames=HM1_2773 {ECO:0000313|EMBL:ABZ85302.1};
OS Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliomicrobium.
OX NCBI_TaxID=498761 {ECO:0000313|EMBL:ABZ85302.1, ECO:0000313|Proteomes:UP000008550};
RN [1] {ECO:0000313|EMBL:ABZ85302.1, ECO:0000313|Proteomes:UP000008550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51547 / Ice1 {ECO:0000313|Proteomes:UP000008550};
RX PubMed=18441057; DOI=10.1128/JB.00299-08;
RA Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT of the Firmicutes containing the simplest photosynthetic apparatus.";
RL J. Bacteriol. 190:4687-4696(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC EC=4.1.1.49; Evidence={ECO:0000256|ARBA:ARBA00001389};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC family. {ECO:0000256|ARBA:ARBA00006052}.
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DR EMBL; CP000930; ABZ85302.1; -; Genomic_DNA.
DR RefSeq; WP_012283784.1; NC_010337.2.
DR AlphaFoldDB; B0TC29; -.
DR STRING; 498761.HM1_2773; -.
DR KEGG; hmo:HM1_2773; -.
DR eggNOG; COG1866; Bacteria.
DR HOGENOM; CLU_536211_0_0_9; -.
DR OrthoDB; 9806325at2; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000008550; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.228.20; -; 1.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR Gene3D; 2.170.8.10; Phosphoenolpyruvate Carboxykinase, domain 2; 1.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR PANTHER; PTHR30031:SF0; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); 1.
DR PANTHER; PTHR30031; PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP; 1.
DR Pfam; PF01293; PEPCK_ATP; 1.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008550}.
SQ SEQUENCE 511 AA; 56945 MW; 5A9D62134D454A30 CRC64;
MHPFRQPLKL ARLIDNPTAA QLREMARGEE QTTEFGSPCY VSKVRNRSAK QTYLVEDGIT
LGVDQQGISL EKATALAAEV HRYLADRGVI RLDRQMGLDA NHTYHCRLYI TEPYARIPAM
WIHSLFAPVD KDKEPDLISI YVPEWPERII FCHPLAGVTY ILGTDYFGEC KKSFLRMAMF
RTKQKGGLGL HAGSKVLRIR DAAGELKDVG FILFGLSGTG KTTLTIHDHG LTGDERVIIR
QDDIVLMDPD GFCAGTEDGF YIKTDGLDKL QKVLYAAALS PNALFENIKV FEGGVIDFFN
QELTSNGRGI VLRREVAGSD DSIDLQKAHK LIFITRRNDI VPPLARLNSV QGAAYFMLGE
SIETSAGDPT KAGQSKREVG TNPFIVGPEA EEGHRLLEIL RNNPDMECYL LNTGSVGARE
GDAGIKLSIE VSTTLMKEIA KGGIEWTVDP DWGYEVPVSV SGLDIEAIMP RRFYSEEEYQ
ARVEKLRVER REWLAHFPGL AEEIRAAVEK A
//
