ID B0TH38_HELMI Unreviewed; 526 AA.
AC B0TH38;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:ABZ83363.1};
GN ORFNames=HM1_1211 {ECO:0000313|EMBL:ABZ83363.1};
OS Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliomicrobium.
OX NCBI_TaxID=498761 {ECO:0000313|EMBL:ABZ83363.1, ECO:0000313|Proteomes:UP000008550};
RN [1] {ECO:0000313|EMBL:ABZ83363.1, ECO:0000313|Proteomes:UP000008550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51547 / Ice1 {ECO:0000313|Proteomes:UP000008550};
RX PubMed=18441057; DOI=10.1128/JB.00299-08;
RA Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT of the Firmicutes containing the simplest photosynthetic apparatus.";
RL J. Bacteriol. 190:4687-4696(2008).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP000930; ABZ83363.1; -; Genomic_DNA.
DR RefSeq; WP_012281895.1; NC_010337.2.
DR AlphaFoldDB; B0TH38; -.
DR STRING; 498761.HM1_1211; -.
DR KEGG; hmo:HM1_1211; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_2_9; -.
DR Proteomes; UP000008550; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ABZ83363.1};
KW Cilium {ECO:0000313|EMBL:ABZ83363.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:ABZ83363.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008550};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..104
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 239..512
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 469..496
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 526 AA; 58103 MW; 22DB5E978D50C225 CRC64;
MTMRIGGLAS GMDIDAMVKE MMKGHVVRRD QIYQKKVQTE WRQTEIIDLN SQLRDFRDAI
FKLKLSNSTS PKSVTSGNSI AVTATATADA ANTSHMVKVK SLAQGVTKGS EAAISATANA
NKNALKTHLG LTSTDVFTMK LNGKEISVDP NKSIYEWVNN INKAGAGVKA NYDVNLDRVF
LYTTEQGPTT KIDFTGTTDA QAQEMIGKLK LGASPTDNWS LDVNGDGTPD NVGYKWVGTA
AEVEIDGITY SNLSKNTLTV AGVVYSFLQK TEGTAEPIVT LQVSPDLEGT VKTVKDFVDK
YNEMLNKLNG ELKEKTYRDF LPLTDEQKRA MKENEIKLWE EKAKSGLLRN ESSLRNLVSQ
MRFAVSDAIG ELKGKYKSLS SIGITTGLYS EGGKLYLNED VLLKALTENP DVVSELFGTT
VTKADPSNPE NKINDLSRSG VAVRLYDRLK EAMDKMRVRA GTLPGADDMS DLGKQLRRYN
KQLDDMEERM HRLENQYYRQ FSALETALQR ANAQSAWLSQ QFGAKG
//
