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Database: UniProt
Entry: B0TUD3
LinkDB: B0TUD3
Original site: B0TUD3 
ID   TRMN6_SHEHH             Reviewed;         246 AA.
AC   B0TUD3;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   01-OCT-2014, entry version 42.
DE   RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
DE            EC=2.1.1.223 {ECO:0000255|HAMAP-Rule:MF_01872};
DE   AltName: Full=tRNA m6A37 methyltransferase {ECO:0000255|HAMAP-Rule:MF_01872};
GN   OrderedLocusNames=Shal_0858;
OS   Shewanella halifaxensis (strain HAW-EB4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=458817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB4;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella halifaxensis HAW-EB4.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the adenine in position 37 of
CC       tRNA(1)(Val) (anticodon cmo5UAC). {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + adenine(37) in
CC       tRNA(1)(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine(37)
CC       in tRNA(1)(Val). {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01872}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. tRNA
CC       (adenine-N(6)-)-methyltransferase family. {ECO:0000255|HAMAP-
CC       Rule:MF_01872}.
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DR   EMBL; CP000931; ABZ75433.1; -; Genomic_DNA.
DR   RefSeq; YP_001673092.1; NC_010334.1.
DR   ProteinModelPortal; B0TUD3; -.
DR   STRING; 458817.Shal_0858; -.
DR   EnsemblBacteria; ABZ75433; ABZ75433; Shal_0858.
DR   GeneID; 5902915; -.
DR   KEGG; shl:Shal_0858; -.
DR   PATRIC; 23504216; VBISheHal24697_0904.
DR   eggNOG; COG4123; -.
DR   HOGENOM; HOG000283147; -.
DR   KO; K15460; -.
DR   OMA; NPPFYAE; -.
DR   OrthoDB; EOG66TGB2; -.
DR   BioCyc; SHAL458817:GH1X-874-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   GO; GO:0016430; F:tRNA (adenine-N6-)-methyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   HAMAP; MF_01872; tRNA_methyltr_YfiC; 1.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR002296; N12N6_MeTrfase.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases-like.
DR   InterPro; IPR022882; tRNA_adenine-N6_MeTrfase.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
FT   CHAIN         1    246       tRNA1(Val) (adenine(37)-N6)-
FT                                methyltransferase.
FT                                /FTId=PRO_0000387421.
SQ   SEQUENCE   246 AA;  27203 MW;  4166B4BD675E71FC CRC64;
     MPFTFKLFHV DDSRCGMPVS TDGVLLGAWA PLVQAKTILD IGAGSGLLSL MAAQRSQAKI
     TAIELDNDAA LDCQQNFDAS HWSERLEIIC CDIQAYCQRE QARQFDHIIC NPPYFANGPQ
     SSKFSRATAR HTDSLSFDAL LQAIKQLLAP EGQASLILPT ESVSLLEAIL STYNLRLCHK
     LLAASVEGKA PNRQILVLGH DLKAKKIHNF GTELQAVAQQ QLYIREKTGH YSLAFTLLSQ
     DFYLKL
//
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