ID   B0VYZ1_CULQU            Unreviewed;       555 AA.
AC   B0VYZ1;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 79.
DE   RecName: Full=IMD domain-containing protein {ECO:0000259|PROSITE:PS51338};
GN   Name=6030909 {ECO:0000313|EnsemblMetazoa:CPIJ000112-PA};
GN   ORFNames=CpipJ_CPIJ000112 {ECO:0000313|EMBL:EDS25735.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS25735.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS25735.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ000112-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ000112-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
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DR   EMBL; DS231813; EDS25735.1; -; Genomic_DNA.
DR   RefSeq; XP_001841782.1; XM_001841730.1.
DR   AlphaFoldDB; B0VYZ1; -.
DR   STRING; 7176.B0VYZ1; -.
DR   EnsemblMetazoa; CPIJ000112-RA; CPIJ000112-PA; CPIJ000112.
DR   KEGG; cqu:CpipJ_CPIJ000112; -.
DR   VEuPathDB; VectorBase:CPIJ000112; -.
DR   eggNOG; ENOG502QRG4; Eukaryota.
DR   HOGENOM; CLU_015065_0_0_1; -.
DR   InParanoid; B0VYZ1; -.
DR   OMA; ESKTNMN; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF4; FI21477P1-RELATED; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          1..192
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   REGION          73..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          224..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..444
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  59621 MW;  59A08B28E596A800 CRC64;
     MCATKEIGTA LTRVCLRHKA VETRMKTFTS AIMECLIVPL QEKLEDWKKQ VAIIDKDHAK
     EYKRCRTELK KRSSDTLRLQ KKAKKGGHHA GGGAGGQDSL HILVESSMQD VTLRRCELEE
     VERKSLRAIM VEERSRYCTF VNMLQPVVHD ECEVMSELSH LQEAMQIIAV VTKDPAILPQ
     ASEELILESK TNMNLYPDSP GGSNSQGGCS NSLGSRKSSV CSISSINSSS SGSPGHQFQR
     SLSQASTLAS QSHAVSTWPP HTQDGTATAD RPHTISSAYE KGHQRPALTV YTFQNPEAIS
     ENNPKSPANI SCRPPLPVQT SSSNSQAMQP LQMGYQQLQQ QPNSPVLSSA SSLISPDSSA
     TNAISSPDVS ACSTQTPQNT PQTGSPQTPI YSSSNSMVLV GTGPSDGVAA GESNGGGGST
     LAEGSAGIES NNDKPKPSSS SPATNDFDDH DHPSNTNNQS QSTTDKDILK CTGSVLEKTS
     MFEQQINNNQ HTAAVLLNTP TRSENSGRKG EDIYKSTGLL SERDAGESEC HLRFVTPLLL
     SSVVADQLHA QLFLA
//