ID B0W065_CULQU Unreviewed; 1650 AA.
AC B0W065;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Ion channel nompc {ECO:0000313|EMBL:EDS37637.1, ECO:0000313|EnsemblMetazoa:CPIJ000429-PA};
GN Name=6031275 {ECO:0000313|EnsemblMetazoa:CPIJ000429-PA};
GN ORFNames=CpipJ_CPIJ000429 {ECO:0000313|EMBL:EDS37637.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS37637.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS37637.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ000429-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ000429-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS231816; EDS37637.1; -; Genomic_DNA.
DR RefSeq; XP_001842099.1; XM_001842047.1.
DR STRING; 7176.B0W065; -.
DR EnsemblMetazoa; CPIJ000429-RA; CPIJ000429-PA; CPIJ000429.
DR KEGG; cqu:CpipJ_CPIJ000429; -.
DR VEuPathDB; VectorBase:CPIJ000429; -.
DR VEuPathDB; VectorBase:CQUJHB014934; -.
DR eggNOG; KOG0508; Eukaryota.
DR eggNOG; KOG3609; Eukaryota.
DR eggNOG; KOG4177; Eukaryota.
DR HOGENOM; CLU_001375_1_0_1; -.
DR InParanoid; B0W065; -.
DR OMA; ANETAMH; -.
DR OrthoDB; 2876723at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 7.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR002153; TRPC_channel.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 8.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 25.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 17.
DR PROSITE; PS50088; ANK_REPEAT; 19.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1152..1173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1185..1207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1219..1238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1250..1270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1290..1314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1321..1341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1442..1463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 148..180
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 181..213
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 214..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 248..280
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 281..313
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 314..346
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 348..381
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 382..414
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 458..499
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 540..572
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 573..605
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 606..633
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 640..672
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 743..775
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 809..842
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 855..877
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 890..917
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 924..956
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 957..989
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1248..1477
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 72..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1650 AA; 180031 MW; 3A34AE95A0BCB273 CRC64;
MSNVVKRFQN VQSKYAKFNP AKAAVLSAAA TGNNGSPEGS ISEAGSRTPT SALGVDFQAA
ILAQNIEVNE AAEPEGTKSG PPQLVPGPVP GPSGQGSVSL RKNSNLGPPR RSVGGPAGKR
NSTVGKSPVQ PRRGGTVAIP SNRATTNNGD TALHLAARRK DVEMARILVD YGANVDLQNG
DGQTALHIAA AEGDEAMVKY FYTVRASASI IDNQDRTPMH LAAENGHASI IEILADKFRA
SIYERTKDGS TLMHIASLNG HAECATTLFK KGVYLHMPNK GGARSIHTAA KYGHVGIIST
LLNKGERVDV PTNDNYTALH IAVQSAKPAV VETLLGFGAE VHVRGGKLRE TPLHIAARVK
DGDRCALMLL KSGAGANKTT DDGQTPVHVA AKYGNVLTMD QLLEDNGDPL VKSKIGETPL
HLGTRNCHPE IVRHLIDFVL EKHGKEVLRN YLNFTNEDGA TAMHYACQIT KDQVKTPNAD
REIVKMLLEN GADVTLSTRS TLETCFHVVS VVGNNDVLSE MIAHLSTTDI QKAMNRQSSV
GWTALLIACN RGHMDLVNTL LANHARVDVF DNEGRSALHL AAEHGYLQVC DALITNKAFI
NSKSRNGRTA LHLAAMNGYT ELVKFLIRDH AAVVDILTLR KQTPLHLAAA SGQMNVCKLL
LELGANIDAT DDVGQKPIHV AAQNNYSEVA KLFLQQHPNL VMATSKDGNT CAHIAAMQGS
VKVIEELMKF DRNGVISTRN KLTDSTPLQL AAEGGHADVV KVLVRAGGSC TDENKSGFTA
VHMAAKNGHG QVLEVMRSTN SLRVSSKKLG LTPLHVAAYY GQADTVRELL INVPATVKSD
SPSGTSLVPE LGNESGLTPL HLAAYSGNEN VVRLLLNSAG VQVDAATTEN GYNPLHLACF
GGHVPIVGLL LSRSAELLHS VDRHGKTGLH IAAMHGHYQM VEVLLGQGSE INASDKNGWT
PLHCTAKAGH LDVVKLLVEA GGSPKSETNY GCAPIWFAAA EGHNDVLRYL MHREHDTYAL
MEDKRFVYNL MIVSKNHNNK PIEEFVLVSP APVDTAAKLS NIFIVLSTKE KERAKDLISA
GKQCETMATE LLALAAGADS AGRILTATDR RNMEFLDVLI ENEQKEVIAH TVVQRYLQEL
WRGTLNWTAW RIMLLFVGFI VCPPVWIIFT LPLGHNYYKV PIIKFMSYLT SHIYLMIHLM
IVGITPIYPV VRASLLPYWY EWGLLVWLSG LLLFELTNPS DKSGLGSIKV LVLLFGVIGV
GVHVSGMLYV QKTYWPTLLY CRNQLFALSF LLACVQILDF LSFHHLFGPW AIIIGDLLKD
LARFLAVLAI FVFGFSMHIV ALNQSFHNLS QDEVRRLPLA TRNKEVFSDD EDDEDLFSDE
VERIKRAAAG QPITDYRRKH KTDIPMTPII AFERLFFAVF GQTSPDDINS QRSTRPEWTE
NLFKIVFGIY MLVSVVVLIN LLIAMMSDTY QRIQAQSDIE WKYGLSKLIR NMHRTSTAPS
PMNLVTTWFV WIVEKIRAKL VKKKRPSLVQ MMNLHRGQQS PRSKAGAKWL SKVKKGQVAP
KDSTAMSAMH LSPLGSQVSF ATVNTTRIEN VADWVEISKK YRALVGIDSE DGGSMKDSEG
DNHSIVAGSQ VNVQAGGGGQ MGNNVNANQV
//
