ID B0W5K0_CULQU Unreviewed; 888 AA.
AC B0W5K0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Transport protein SEC24 {ECO:0000313|EMBL:EDS35483.1};
GN Name=6033552 {ECO:0000313|EnsemblMetazoa:CPIJ002315-PA};
GN ORFNames=CpipJ_CPIJ002315 {ECO:0000313|EMBL:EDS35483.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS35483.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS35483.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ002315-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ002315-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR EMBL; DS231843; EDS35483.1; -; Genomic_DNA.
DR RefSeq; XP_001843984.1; XM_001843932.1.
DR AlphaFoldDB; B0W5K0; -.
DR STRING; 7176.B0W5K0; -.
DR EnsemblMetazoa; CPIJ002315-RA; CPIJ002315-PA; CPIJ002315.
DR KEGG; cqu:CpipJ_CPIJ002315; -.
DR VEuPathDB; VectorBase:CPIJ002315; -.
DR VEuPathDB; VectorBase:CQUJHB016425; -.
DR eggNOG; KOG1985; Eukaryota.
DR HOGENOM; CLU_004589_2_0_1; -.
DR InParanoid; B0W5K0; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF39; SECRETORY 24AB, ISOFORM A; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 345..381
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 418..640
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 651..735
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 746..847
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT REGION 1..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 98236 MW; B1F4BF49FAA490C8 CRC64;
MANGYPPVAN GPAMHQPQQF PPPQQQQQHQ QQYPVKTALM NGPSSQQQYG APPVAAVAPL
QNGPPPQMMM GQKVSPPFNN TQQQNNRVAN LVSNGNSATS SRTSSPALVN NNIPASQLPP
RSVPPGVTYQ PPSSQSQTTP VVSSNYQLSP NNNWASGINT SNQVNTPPRN ASGLSTPLNA
STPTVNGPSA VNNLTASMQN LAVNRPHSAQ QVNHLNGSGT PQPPPTVPTS SYQNQLPPSQ
PTSMKPNVQQ YNVVKSGFNR LWGNNTMDLL QNRHVLPPGK VRPPVIHLNH PFQEAVNCNP
DIFRCTLTKI PETNQLLQKS RLPLGVLIHP FRDLNNLPVI SCNTIVRCRT CRTYINPFVF
FVDSKKWKCN LCYRVNELPE EFQYDPVTKT YGDPTRRPEV KSSTIEFIAP SEYMLRPPQP
AIYLFLLDVS SLAQQTGYLH TVCRTLIEHL DSLPGDARTQ VGFIAYNSAI HFYNIAEGYN
QPHEVTVLDV DDVFLPYPDN LLINLKECKE LVKDLLTQLP KRFEHAHDTH SALGAALQVA
YKMMCHTGGR VTVFQTCLPN HGPGALQSRE DPNNRSSKDV AHLGPATDFY KRLALDCSAQ
QIAVDLFLLN TGISKFSGGC MHHIPLYCES KPQLVKTLQK CFERYLTRKV GFEAVMRVRC
TRGLAIHTFH GNFFVRSTDL LSLPNVNPDA GFGMQITYEE SLAECKTVCF QAALLYTSSK
AERRIRVHTL CIPVTASLSE VMYSADSQCI VGLLSKMAVD RSLTSSLSDA RDAFINATVD
IFSAFKIAQN LPQNSGSIVA PENLSLLPLY ILALLKHTAF RVGTSTRLDD RVFAMSEMKT
MPLDQLIRYI YPDFYVLDSL FHSATQEHSG NGEAHLVEPP RLQLSAEK
//
