ID   B0W5Y1_CULQU            Unreviewed;       556 AA.
AC   B0W5Y1;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN   Name=6033690 {ECO:0000313|EnsemblMetazoa:CPIJ002371-PA};
GN   ORFNames=CpipJ_CPIJ002371 {ECO:0000313|EMBL:EDS35968.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS35968.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS35968.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ002371-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ002371-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
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DR   EMBL; DS231845; EDS35968.1; -; Genomic_DNA.
DR   RefSeq; XP_001844115.1; XM_001844063.1.
DR   AlphaFoldDB; B0W5Y1; -.
DR   STRING; 7176.B0W5Y1; -.
DR   EnsemblMetazoa; CPIJ002371-RA; CPIJ002371-PA; CPIJ002371.
DR   KEGG; cqu:CpipJ_CPIJ002371; -.
DR   VEuPathDB; VectorBase:CPIJ002371; -.
DR   VEuPathDB; VectorBase:CQUJHB017589; -.
DR   HOGENOM; CLU_490262_0_0_1; -.
DR   InParanoid; B0W5Y1; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00590; RRM_SF; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR48034:SF6; RIBONUCLEOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05260)-RELATED; 1.
DR   PANTHER; PTHR48034; TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          402..495
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          118..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..156
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..240
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..324
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   556 AA;  63880 MW;  60F87501D74468BB CRC64;
     MQVVEVQMNN IQAFSQMPMI EQFNLVHGIV NQFINFPQFV GLSADAKISY LISGQQTMIS
     IIQADFLKTV SAPSVVPPNE APVPGQPNPS QENVESIIDN DGVLAPWQTM KKTKMVITNK
     EKSPISEEIS AQDRFEEAER LRNASEPTEE KEEVQIQETL SVSSGSDSIP PAPAPPIIDL
     AKSRSRSKSP MTLPTQYCRV ARRRKSRSPR RKSRHRSRSP RGRRSRSPVR ARRRSPSPRS
     RRRLSPISRA LESRPISHIS RRRRSLSKSP RRYTRDRSPA RRRSHRRDSP PARSVRRSRT
     RSPRPHRRHI SPPARRHSPI RRPSPVRRRS PSIVRSKSRS HSLSPLWDEE VALDEMSLDD
     FTHERSASLS LSPISDRGSP FDEDIADDRG HSAEPIGSTN DRTLFVNNLP YDTTDADLEE
     LFGKYGEVVS HRFVEHPQNF ETKRAYVTFD TLDQAVRGLD LHLKRHRQLL LRVAFVNKRQ
     MWRAGFAVNV TVAKDYDELP IYETFKMCGE ITCLWTRLFN SKKYCVIDFK HRDAVPIALE
     VRQLHNGWKC RVTAII
//