ID   B0W9G5_CULQU            Unreviewed;       471 AA.
AC   B0W9G5;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Coagulation factor IX {ECO:0000313|EMBL:EDS40190.1};
GN   Name=6035113 {ECO:0000313|EnsemblMetazoa:CPIJ003776-PA};
GN   ORFNames=CpipJ_CPIJ003776 {ECO:0000313|EMBL:EDS40190.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS40190.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS40190.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ003776-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ003776-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC       {ECO:0000256|ARBA:ARBA00024195}.
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DR   EMBL; DS231864; EDS40190.1; -; Genomic_DNA.
DR   RefSeq; XP_001845349.1; XM_001845297.1.
DR   AlphaFoldDB; B0W9G5; -.
DR   EnsemblMetazoa; CPIJ003776-RA; CPIJ003776-PA; CPIJ003776.
DR   KEGG; cqu:CpipJ_CPIJ003776; -.
DR   VEuPathDB; VectorBase:CPIJ003776; -.
DR   VEuPathDB; VectorBase:CQUJHB001391; -.
DR   eggNOG; KOG3627; Eukaryota.
DR   HOGENOM; CLU_004497_6_1_1; -.
DR   InParanoid; B0W9G5; -.
DR   OrthoDB; 5305860at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 4.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001254; Trypsin_dom.
DR   PANTHER; PTHR24260; -; 1.
DR   PANTHER; PTHR24260:SF148; SERINE PROTEASE GRASS; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   SMART; SM00020; Tryp_SPc; 2.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 2.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..471
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011407667"
FT   DOMAIN          36..222
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   DOMAIN          230..442
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   471 AA;  52431 MW;  8216CA139D37B48B CRC64;
     MAVFILEVCI FLLMVFYGEA TVCGVPRINS SLLSSNEGGG TYPGQWPWHV AIYQRPKNQS
     FLAYKAGGTL ISSTFVLTAG ACRLSEVDRH YMYPSAHYIR VGIHNLNVLS LGTGQYRSVE
     RFHFPYHWNK MKAVMITLVE LRREVQFNDL VQPVCIFYNQ VSSRIKSGTV VGWGPTKNDH
     EAVQISRQLS VHDDDCLRLG GPYNAIRNIS LFCVGSPNGT DCGSFIWDGV IKGQTAPLFA
     YPWMALLARR DLLSRDAIEY VCDGSLISNR YVLTNSRCTA VKEPPELVRL GEHTMGQDID
     CNANDDTDCA PPVRDYPIQF IVTHQNEHMG DSIALVRLNQ DVTFEDHIQP ICLPVTPELR
     ALQLDQFIVT GWGSSAGTLR QATLESTTSC DDDAREGSPV GYPVRHRGVR FVQLGVMTGC
     ERGLPVYANV SRLMDWIVVN TDARNTKPAP PKPERVGILC CKQGLNVAEN Q
//