ID B0WF65_CULQU Unreviewed; 710 AA.
AC B0WF65;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Sulfate transporter {ECO:0000313|EMBL:EDS26041.1};
GN Name=6037431 {ECO:0000313|EnsemblMetazoa:CPIJ006006-PA};
GN ORFNames=CpipJ_CPIJ006006 {ECO:0000313|EMBL:EDS26041.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS26041.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS26041.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ006006-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ006006-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; DS231915; EDS26041.1; -; Genomic_DNA.
DR RefSeq; XP_001847349.1; XM_001847297.1.
DR AlphaFoldDB; B0WF65; -.
DR STRING; 7176.B0WF65; -.
DR EnsemblMetazoa; CPIJ006006-RA; CPIJ006006-PA; CPIJ006006.
DR KEGG; cqu:CpipJ_CPIJ006006; -.
DR VEuPathDB; VectorBase:CPIJ006006; -.
DR VEuPathDB; VectorBase:CQUJHB015999; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_9_2_1; -.
DR InParanoid; B0WF65; -.
DR OMA; NRVEHFD; -.
DR OrthoDB; 1067648at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 143..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 231..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 310..329
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 388..416
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 502..531
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 564..689
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 76204 MW; FE2B1959A1A8E530 CRC64;
MSKKGHFDPR FNIGGGVAGG GGGGNAGDGL TNRGFYQDLT DDGGRSLDAT DSSEKLPQLT
VARPHYQQEE LNNEMNYRKP KTRMCQTVLA GVKSFSARRC LGNVLPIFNW LSEYSWERDF
LADLISGCTV AVMHIPQGMG YALLANVPPI VGIYMAFFPV LIYFLLGTSR HNSMGTFAVI
SIMVGKSVLA HSTAGAALKM AESGVGNGTE GGGGGVTVAD VALPGRGPIE VAAAVCFIVG
AMQLLMYVCR LGVVSFLLSD TLVSGFTTGA AIHVLTSQIK DLLGLSLPPI TGNFKIVNTY
IAIFSDIARV NYSAILISTV TIVLIVINNE FLKPKVAKRS AIPIPIELIA VISGTLLSQY
LGLNEQYAIK TIGHIPTGFP APSLPDLALF RVLLLDCFTI AMVAYAVSVS MGLIFAQKQN
YEIDFNQELL AMGASNVFGS FFSCMPFSAS LSRSMIQFTV GGKTQIASII SGDHRGVAEG
TADAGDSICG LLAVELRGRA RWMVTFLTVV LIAIDIGLLV GIALSVIFIF LKGMKPYTCL
MENVPNTDLY LDVKRYKGTI DIAGVKIFHF CGSLNFATRA GFKSSLCQLL NINLTEEIKQ
LNSGDYKRQQ NLLRCLVLDF TAVSYIDTSA VSSLKSLINE FDKLSIKILV AGAPCPVYEM
MLKCKLVGPA VEREYCKVFP TVHDAVHWGK ECIAQDSGRI SVVGLEGGVV
//
