ID B0WFI8_CULQU Unreviewed; 849 AA.
AC B0WFI8;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE SubName: Full=Nad dehydrogenase {ECO:0000313|EMBL:EDS26256.1, ECO:0000313|EnsemblMetazoa:CPIJ006058-PA};
GN Name=6037576 {ECO:0000313|EnsemblMetazoa:CPIJ006058-PA};
GN ORFNames=CpipJ_CPIJ006058 {ECO:0000313|EMBL:EDS26256.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS26256.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS26256.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ006058-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ006058-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LanC-like protein family.
CC {ECO:0000256|ARBA:ARBA00007179}.
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DR EMBL; DS231918; EDS26256.1; -; Genomic_DNA.
DR RefSeq; XP_001847472.1; XM_001847420.1.
DR AlphaFoldDB; B0WFI8; -.
DR EnsemblMetazoa; CPIJ006058-RA; CPIJ006058-PA; CPIJ006058.
DR GeneID; 6037576; -.
DR KEGG; cqu:CpipJ_CPIJ006058; -.
DR VEuPathDB; VectorBase:CPIJ006058; -.
DR VEuPathDB; VectorBase:CQUJHB014997; -.
DR eggNOG; KOG2787; Eukaryota.
DR eggNOG; KOG2844; Eukaryota.
DR HOGENOM; CLU_335939_0_0_1; -.
DR InParanoid; B0WFI8; -.
DR OrthoDB; 1377744at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR CDD; cd04794; euk_LANCL; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR007822; LANC-like.
DR InterPro; IPR020464; LanC-like_prot_euk.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR12736; LANC-LIKE PROTEIN; 1.
DR PANTHER; PTHR12736:SF7; LANC-LIKE PROTEIN 3; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF05147; LANC_like; 1.
DR PRINTS; PR01951; LANCEUKARYTE.
DR PRINTS; PR01950; LANCSUPER.
DR SMART; SM01260; LANC_like; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF158745; LanC-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT DOMAIN 399..758
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 761..817
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
SQ SEQUENCE 849 AA; 94732 MW; 8A66BF21832B3727 CRC64;
MSSRHFDNPF EDYDASKHGG ADETTLLDKP LILKLVKDYV ERILTGSGKS DYKLRADLYV
GEAGIAYMFW KLSRSKELKD LFPCLEHARH FIQRAKEIAA ASSKSSRTSR VAFLCGNAGV
AAVSAVIAHD LGEQDDAQRE LHRFHEGHSV AVSGGYDADE ILVGRAGYLS GAFWLNQVLP
AKPIKRAEIE AVCVVLLKRG REYAKARRCA VPLMYEYHES DYLGAAHGLC SILHMLLESP
WFGEGSGASE TKLADIRGSV EAFLEIQDEN GNFPTRLVGS DKKLTHWCHG CSGAIYLLAR
AYLVFEEEKY LAGCRKCADS IWRHGLLYKG PGICHGVAGN GYAFLLMYRL TGEKRYLYRA
GKFAEFLSAE CFVANARTPD RPFSLHFSGT AAVSQTAARV VIAGAGLLGN SVAYHLTQNG
WNNVIVLDQR TIGSGTSDFG SGTIGLFKPS PERNIILESV KLYERLQRAG HNVGLKRCGS
LNLAQTHDRV VALKRRIAYN MPAGLYCELI DAETVRNLHP LLNVDDIQGA VYVPKDCIAD
PALVLEVLAK LSKQAGVKYF ENCRVEFVNT KGGRVESLET DIGTIKCEYF INCTGMWSRE
LGLRCKRPVR IPAYPAQHFF AVTAGLNLPE AKLLPCVRDY DSNMYARQLG SEMMVGWFEK
AAKPAFENIK DIPKNWKEHI EDSAPNHWEP LWDKAVDRIP LLTDSGAPTI TNSPDNFTPD
GRWIFGETAE VKNYYVACGM NGNPLQGSGG VGKALAEWIV NGTPTIEMLP FNIQRFLDLH
NNRQYLQHRI REVVGRQYAI LYPNQSEYKF ARQLRCSPLY SELETRGAVF GTKMAYERAL
YFDSDYERK
//
