ID   B0WIW8_CULQU            Unreviewed;       438 AA.
AC   B0WIW8;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Chitobiosyldiphosphodolichol beta-mannosyltransferase {ECO:0000313|EMBL:EDS28794.1, ECO:0000313|EnsemblMetazoa:CPIJ007482-PA};
GN   Name=6038963 {ECO:0000313|EnsemblMetazoa:CPIJ007482-PA};
GN   ORFNames=CpipJ_CPIJ007482 {ECO:0000313|EMBL:EDS28794.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS28794.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS28794.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ007482-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ007482-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|ARBA:ARBA00004922}.
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DR   EMBL; DS231953; EDS28794.1; -; Genomic_DNA.
DR   RefSeq; XP_001848652.1; XM_001848600.1.
DR   AlphaFoldDB; B0WIW8; -.
DR   STRING; 7176.B0WIW8; -.
DR   EnsemblMetazoa; CPIJ007482-RA; CPIJ007482-PA; CPIJ007482.
DR   KEGG; cqu:CpipJ_CPIJ007482; -.
DR   VEuPathDB; VectorBase:CPIJ007482; -.
DR   VEuPathDB; VectorBase:CQUJHB016646; -.
DR   eggNOG; KOG2941; Eukaryota.
DR   HOGENOM; CLU_012079_0_0_1; -.
DR   InParanoid; B0WIW8; -.
DR   OMA; CKLIIDW; -.
DR   OrthoDB; 1219598at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000030; F:mannosyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR026051; ALG1-like.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   PANTHER; PTHR13036; BETA1,4 MANNOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR13036:SF0; CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:EDS28794.1}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EDS28794.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          248..398
FT                   /note="Glycosyl transferase family 1"
FT                   /evidence="ECO:0000259|Pfam:PF00534"
SQ   SEQUENCE   438 AA;  49925 MW;  0F5C41672845F78A CRC64;
     MKNVPVTIEH ACVVVLGDIG RSPRMQYHAK SLAESRYLVD LIGYVESKPL EDLTSSANVK
     IHRLNPFPEL NLPSVLKYVF KSLWQALTLL VALISIHKPR FVLCQNPPAI PTLVVVYVYC
     LVTRSKMIVD WHNYTHSILA ISTSPDGFIV RLAKAIEFHF GRKAAAGFCV TKAMQADLED
     NWNVRATVLY DRPPVQFHPI PLEEKHALLM RLCNTIGEFM PDSFDAYKDT GVQEATAFTV
     RTADGEVKSR PHRPAMLLSS TSWTPDEDFS MLVSALDIYE KKSLKEPQHY PRLICIITGK
     GPLKEHYKNV IQRKQWQKVS VVTPWLENDD YPKLLACADL GVCLHYSSSG LDLPMKVVDM
     FGSGLPVIEE LVQHGKNGFL FDNYQELSEQ IGEWLYDFPT NIALTNQREV INQNLKEFQQ
     LRWTENWKRT VQPVLESL
//