ID B0WS49_CULQU Unreviewed; 551 AA.
AC B0WS49;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=RUN and FYVE domain containing protein 1 {ECO:0000313|EMBL:EDS33668.1, ECO:0000313|EnsemblMetazoa:CPIJ009735-PA};
GN Name=6042413 {ECO:0000313|EnsemblMetazoa:CPIJ009735-PA};
GN ORFNames=CpipJ_CPIJ009735 {ECO:0000313|EMBL:EDS33668.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS33668.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS33668.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ009735-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ009735-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232064; EDS33668.1; -; Genomic_DNA.
DR RefSeq; XP_001851533.1; XM_001851481.1.
DR AlphaFoldDB; B0WS49; -.
DR EnsemblMetazoa; CPIJ009735-RA; CPIJ009735-PA; CPIJ009735.
DR KEGG; cqu:CpipJ_CPIJ009735; -.
DR VEuPathDB; VectorBase:CPIJ009735; -.
DR VEuPathDB; VectorBase:CQUJHB014212; -.
DR eggNOG; KOG4381; Eukaryota.
DR HOGENOM; CLU_014576_0_1_1; -.
DR InParanoid; B0WS49; -.
DR OMA; KNDMISR; -.
DR OrthoDB; 5385125at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR CDD; cd17681; RUN_RUFY1_like; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR047335; RUFY1-3.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR PANTHER; PTHR45956; RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN; 1.
DR PANTHER; PTHR45956:SF6; RUN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT DOMAIN 86..219
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 239..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 374..401
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 465..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 61355 MW; E5E0471043502D80 CRC64;
MDREAFERGS YTWRVLKGIH SEMMVRESSS NWVLGRGISE EIPTSSSEQL PARDPASIER
SNLVNICKLV VKELLEQSIR FGRMLDSDHL PLQHFFIVLE HVLRHGLRPK KGLLGPKKEL
WDILQSVERY CVEAQDITSS VRDLPTVRTH MGRARAWLRL ALMQKKLADY LQILIERRDD
TLAEYYEPHA LMMSDEVIVI IGILVGLNVI DCNLCVKEED LDSQQGVIDF SLYLRSSSRN
SPDDEHNNGG GNGTVSSIEG TATGAMTAVL DQKNYIEELN RHLNATVGNL QAKVEGLTTT
NALMKEDLAI ARNSLLALQA ENAALRRASQ HGQPLEDKAN VLDRFDPEMA EALAEERKKR
QDIEKELDLQ VSLKAETEMA MKLLEKDIHE KQDTIVSLRR QLEDIKSINL DMYRKLQECE
EELTQKGEMV TRLQVKASQI GKILSNLERK GAADAMTDSQ MSTFSSLTQD SSSGVSSAIG
PPSKKAHLRV GAIPPFNANK LRKSPSVGAS TATTTTKPID EISKTVPTVE PATATDSSED
PKPVQDPPKA D
//
