ID   B0WVT6_CULQU            Unreviewed;       398 AA.
AC   B0WVT6;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 91.
DE   SubName: Full=Chitotriosidase-1 {ECO:0000313|EMBL:EDS35768.1};
GN   Name=6043925 {ECO:0000313|EnsemblMetazoa:CPIJ011495-PA};
GN   ORFNames=CpipJ_CPIJ011495 {ECO:0000313|EMBL:EDS35768.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS35768.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS35768.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ011495-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ011495-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC       {ECO:0000256|RuleBase:RU004453}.
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DR   EMBL; DS232132; EDS35768.1; -; Genomic_DNA.
DR   RefSeq; XP_001861508.1; XM_001861473.1.
DR   AlphaFoldDB; B0WVT6; -.
DR   STRING; 7176.B0WVT6; -.
DR   EnsemblMetazoa; CPIJ011495-RA; CPIJ011495-PA; CPIJ011495.
DR   KEGG; cqu:CpipJ_CPIJ011495; -.
DR   VEuPathDB; VectorBase:CPIJ011495; -.
DR   VEuPathDB; VectorBase:CQUJHB002614; -.
DR   eggNOG; KOG2806; Eukaryota.
DR   HOGENOM; CLU_002833_3_0_1; -.
DR   InParanoid; B0WVT6; -.
DR   OMA; ENPCLKV; -.
DR   OrthoDB; 2663738at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02872; GH18_chitolectin_chitotriosidase; 1.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF398; CHITINASE 2-RELATED; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   PROSITE; PS01095; GH18_1; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..398
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011408604"
FT   DOMAIN          29..397
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
SQ   SEQUENCE   398 AA;  44411 MW;  C9123852D0075897 CRC64;
     MQSILFLISL VILHKILIVE SQACKQKPYN VVCYLASWSV YREGRGSFNV SYVIPTYCTH
     LVYTFAGLGL NGGLDSLDHY NDINVNSLHR QLEGYERIVG LKEENPCLKV MLAVGGWNEG
     SEKYSLMAET EESRMDFADH ALKYLAHFGF DGLDLDWEYP TMRGGIPEDK ENFILLLKTL
     RDKFQRRKKL LSVAIGGSPG IIQAAYDLTA MCEVLDFINL MAYDYGLKNI ASVDAPLYPE
     PTTKSESADG AIAFIRQSGC PMSKINLGIP TRAKTYTLRT GVKGDLRTGI AVQGPGRAGP
     YTKNAGTLGY NELCEMVKEG KWDTKLLNNV KVKVGFHGDQ WVTYDDGETT TAKAMYAKEK
     GLGGVMFWTI DTDDYHGDCH NEAYPMVRAA NRVFGYIR
//