ID B0X763_CULQU Unreviewed; 751 AA.
AC B0X763;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Wsck {ECO:0000313|EMBL:EDS41757.1, ECO:0000313|EnsemblMetazoa:CPIJ015076-PA};
GN Name=6048590 {ECO:0000313|EnsemblMetazoa:CPIJ015076-PA};
GN ORFNames=CpipJ_CPIJ015076 {ECO:0000313|EMBL:EDS41757.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS41757.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS41757.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ015076-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ015076-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; DS232440; EDS41757.1; -; Genomic_DNA.
DR RefSeq; XP_001865485.1; XM_001865450.1.
DR AlphaFoldDB; B0X763; -.
DR STRING; 7176.B0X763; -.
DR EnsemblMetazoa; CPIJ015076-RA; CPIJ015076-PA; CPIJ015076.
DR KEGG; cqu:CpipJ_CPIJ015076; -.
DR VEuPathDB; VectorBase:CPIJ015076; -.
DR VEuPathDB; VectorBase:CQUJHB011618; -.
DR eggNOG; KOG0200; Eukaryota.
DR eggNOG; KOG4228; Eukaryota.
DR HOGENOM; CLU_021662_0_0_1; -.
DR InParanoid; B0X763; -.
DR OMA; WIYELAS; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProt.
DR GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00192; PTKc; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR002889; WSC_carb-bd.
DR PANTHER; PTHR24418:SF421; INACTIVE TYROSINE-PROTEIN KINASE WSCK-RELATED; 1.
DR PANTHER; PTHR24418; TYROSINE-PROTEIN KINASE; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF01822; WSC; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00321; WSC; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS51212; WSC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 371..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..117
FT /note="WSC"
FT /evidence="ECO:0000259|PROSITE:PS51212"
FT DOMAIN 123..223
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 462..727
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 751 AA; 85064 MW; 5EDAA4A35E049431 CRC64;
MVIRRKGSSS SVALLVGVAI VTGCGLVAAS SQRGFFFGCY QRDRSGQLEI ITDQYDRCVS
HCESNYFRYA ALSDTQCMCL NSIRTRVIED KECDLRCRQN PDQTCGGANA QSFYETGVEV
AGPVKNLHLT DKESENTIKI AWSAPALDGV PVLSYEIGAQ ALATYASYRL YPMSWTVHNN
TIAFELSNLT PGTRYNITVS TVSERGTGGM QWLTAQTEIG KPDPEPEEPL ILRRLDSTIQ
IEIPKATNDN GPINYYRVVV HYVNDDLVQQ FDEALLDTFQ RSKEKGVPYY IAAEVTMEGD
SLLFTVGDGK YHRQFFNPPI PPRAHVHISI GIVSILNNVF KVRYATTTHE QHQHPDHHHV
NSTTAPERNE ALITVLTVAC VLFGIVLLAS IVLYVYLRYK TPGNTRPMND HHEMALQGPI
LEVENNGYMP DIYEQRGFEA ELHDIIDSLE SWQKHGRKFL SLEINNVIGS GKYGDVLKGR
LQREGVDMPT QVHVISDDMD KIDQIAFLNE FRRNIKLEDH PNVLQFYGVC VTPDWCYVLF
EEIQTTLKQT LLNARIPTNV NSPKFSTISE EIIVNILCLV CDGMQFLVEN NIINKKLCAR
TVYVNTKFEV KVSGFGPPLY GEDNQQIEIT RWNAPEVIKF QNHTVKSDIW SFGLLIWECC
CLGATPFGTT TIDNLFAAVR SGGRPEKPAF IFDDLYQMCL NCWDLDAGDR PEFDDISRYL
RQTLPMLRYM LSFERTQNVQ LPPYLPHLEL K
//
