ID B0X7G2_CULQU Unreviewed; 892 AA.
AC B0X7G2;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 89.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN Name=6048706 {ECO:0000313|EnsemblMetazoa:CPIJ015478-PA};
GN ORFNames=CpipJ_CPIJ015478 {ECO:0000313|EMBL:EDS41912.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS41912.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS41912.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ015478-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ015478-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS232451; EDS41912.1; -; Genomic_DNA.
DR RefSeq; XP_001865584.1; XM_001865549.1.
DR AlphaFoldDB; B0X7G2; -.
DR STRING; 7176.B0X7G2; -.
DR EnsemblMetazoa; CPIJ015478-RA; CPIJ015478-PA; CPIJ015478.
DR GeneID; 6048706; -.
DR KEGG; cqu:CpipJ_CPIJ015478; -.
DR VEuPathDB; VectorBase:CPIJ015478; -.
DR VEuPathDB; VectorBase:CQUJHB008831; -.
DR eggNOG; KOG0128; Eukaryota.
DR HOGENOM; CLU_007172_1_0_1; -.
DR InParanoid; B0X7G2; -.
DR OMA; LWARYIL; -.
DR OrthoDB; 2879516at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR17204:SF25; EMBRYO DEFECTIVE 140; 1.
DR PANTHER; PTHR17204; PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; 1.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00386; HAT; 6.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 636..725
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 729..806
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..597
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 101784 MW; 9E224FA9267B6705 CRC64;
MSDSEMKVVE EEKDEPMDAP EGEQTEAQTG ETGSSDSDSM DESDEDEDDD DGEALLIKQY
VEQLAKIDED KFNYDNYVQL LEIAHKMTDL DKIRQSAEIF AEAYPLSPEI WLRWLKIEVA
IGNSPDELRQ ADRLFRRALG DYYSVEVAQE YANLATKADA ELADTIWDAL IPAYGLHVTK
GRTIFEAYRE DHLAKNGDGP EQLNRLARIY EQELKIPLRN MEDSHIEYKL LCEKHKAVLV
DLNPEKFERR YRQAKDLLQK MMPYENRLAA LEPHCHQERA DLYREYIREC RSQLEDDDLQ
VLYERSCTDC CLDPTVWTDY LKYLDKYPPD PDEAEASPVF AQSVLDVVNR ALRNCPWSAE
LYVEKMRICE REKRGKADIL KIMEEVATVE FQAPEPAVKV WLEYLTYLRR HADFENEKER
EILRSNFELA WNQLGRTWGE LADPECKILQ FWGRLEYGAL KDPLKGRDLW QSVMDSSDNS
TRVGLWIEYA ELEATRGLDA VRKLYRKAIG SIALNDPETL AAAWMRFERV NGSLEQLTTC
QELCVAKVQE FYKSLGNQKP PKGRRSDPKK DADQNDSPKK KPIKRTHDEH EFKKPAVPSL
PRQKPEPTIE ENTKRIRLEE EPIPAKPEID PTKDVKRVFI SNLSFDATED QIRACFPELN
FKSIELVQSS SGKSRGFGYA ELNHEADVQK ALSFDRRPLN GRPVFISSLA RDKSARPNKF
KYSERFEPNK LFVKGLPFEA TPDDIRKLFE PHGKLKDVRV VYYRSGKSKG LAYVEYESEA
AAKSAVVHMD QYCMDGFTIS VDLSAPPPRG NPTMTATTSG GAPDADAGGS SLGGGKRHVV
KGDVKQKLST LIPTALLRKT TVSTPAGQVP TGSATPSAKP KSNEDFRKML LK
//
