ID B0X7M7_CULQU Unreviewed; 679 AA.
AC B0X7M7;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
GN Name=6048798 {ECO:0000313|EnsemblMetazoa:CPIJ015660-PA};
GN ORFNames=CpipJ_CPIJ015660 {ECO:0000313|EMBL:EDS42039.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS42039.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS42039.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ015660-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ015660-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR EMBL; DS232456; EDS42039.1; -; Genomic_DNA.
DR RefSeq; XP_001865649.1; XM_001865614.1.
DR AlphaFoldDB; B0X7M7; -.
DR EnsemblMetazoa; CPIJ015660-RA; CPIJ015660-PA; CPIJ015660.
DR KEGG; cqu:CpipJ_CPIJ015660; -.
DR VEuPathDB; VectorBase:CPIJ015660; -.
DR VEuPathDB; VectorBase:CQUJHB003560; -.
DR eggNOG; KOG4418; Eukaryota.
DR HOGENOM; CLU_018068_1_0_1; -.
DR InParanoid; B0X7M7; -.
DR OMA; AIEFNFH; -.
DR OrthoDB; 3430189at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15293; 7tmC_GPR158-like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR043458; GPR158/179.
DR PANTHER; PTHR32546; G-PROTEIN COUPLED RECEPTOR 158-RELATED; 1.
DR PANTHER; PTHR32546:SF16; G-PROTEIN COUPLED RECEPTOR CG31760-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 381..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 574..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 383..630
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 679 AA; 76808 MW; 71B72F51733F1696 CRC64;
MLTYMRVNEA IEDSLQTIHD IATENLGTLC LTKQFRPLRI TLNPERYAGA RQKADLAAVV
LQDVGVARHS GLLDALAKGL LSDQHVTSAR ILSINMSDGM VANSVWWNKP TSGMAGPIRT
EEEGIAIGKS PDPSYPWFED ESSSPGLRSP KFAPSPLNIS YRGWWTYPYY SCTHKRWILS
YSVAIPPMGR HGLRGFLSID IDISDLQVNQ CDNANKLEIM SYNYHLRQYY PFVRNIKLSE
ENEQLNQIEA FHGSHKCHVH SMRCVYRPVS VTAAAINMNY NHYSNTSSFT NATGGSGAAM
ISKSLRIIQG WTRGAYECKC RDGFYSLPHP QGFNGSIMEV AFQEYRDNIS SYYMDVFVCV
RCAPGCATCT GPEPCLASYN WVFRTTLLTF SVMCAGFTVV LVLYMYQHRK VKVFKVASPI
FLTITLLGCA FMYLEMAAIF PILDTYSCIA TKWTRHMGFC VTYTALLMKT WRVSLTYRVK
SAHKVKLTDK QLLQWMVPIL LVMLIYLGTW TLSAPPTAEK IVDQNGLIFK QCSYNWWDHS
LAIGEVLFLA WGIRVCYNVR NAESLYNEAR LISYAIYNIA LVNTTMVAFH LFFFPQAGPD
IKYLLGFLRT QLSTSVTIAL VFGPKVLRIL RGQGDQWDQR ARKRGITASF SLNGIGLVPE
ETADLYQENE ELKVGRKMD
//
