GenomeNet

Database: UniProt
Entry: B0X7X7_CULQU
LinkDB: B0X7X7_CULQU
Original site: B0X7X7_CULQU 
ID   B0X7X7_CULQU            Unreviewed;       375 AA.
AC   B0X7X7;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   20-DEC-2017, entry version 65.
DE   SubName: Full=Hepatic triacylglycerol lipase {ECO:0000313|EMBL:EDS42196.1};
DE   SubName: Full=Hepatic triacylglycerol lipase precursor {ECO:0000313|VectorBase:CPIJ015386-PA};
GN   Name=6048904 {ECO:0000313|VectorBase:CPIJ015386-PA};
GN   ORFNames=CpipJ_CPIJ015386 {ECO:0000313|EMBL:EDS42196.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDS42196.1, ECO:0000313|VectorBase:CPIJ015386-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS42196.1,
RC   ECO:0000313|VectorBase:CPIJ015386-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ015386-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ015386-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00553472}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase
CC       family. {ECO:0000256|RuleBase:RU004262,
CC       ECO:0000256|SAAS:SAAS00591292}.
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DR   EMBL; DS232468; EDS42196.1; -; Genomic_DNA.
DR   RefSeq; XP_001865749.1; XM_001865714.1.
DR   UniGene; Cpi.7277; -.
DR   ProteinModelPortal; B0X7X7; -.
DR   EnsemblMetazoa; CPIJ015386-RA; CPIJ015386-PA; CPIJ015386.
DR   GeneID; 6048904; -.
DR   KEGG; cqu:CpipJ_CPIJ015386; -.
DR   VectorBase; CPIJ015386-RA; CPIJ015386-PA; CPIJ015386.
DR   eggNOG; ENOG410JNRY; Eukaryota.
DR   eggNOG; ENOG410ZKWM; LUCA.
DR   HOGENOM; HOG000038551; -.
DR   InParanoid; B0X7X7; -.
DR   OrthoDB; EOG091G09EC; -.
DR   PhylomeDB; B0X7X7; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00707; Pancreat_lipase_like; 1.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase/vitellogenin.
DR   InterPro; IPR033906; Lipase_N.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610; PTHR11610; 1.
DR   Pfam; PF00151; Lipase; 1.
DR   PRINTS; PR00821; TAGLIPASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00709807};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Secreted {ECO:0000256|SAAS:SAAS00439306};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    375       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5011409047.
FT   DOMAIN       91    370       Lipase. {ECO:0000259|Pfam:PF00151}.
SQ   SEQUENCE   375 AA;  40393 MW;  AF4BF56C03B7E687 CRC64;
     MKLLLALVLA VSTLHAVRGF DFGDLAKKTG DVAKVAVKTT KTLVEKAPEI FSPEQLLEFG
     KQSIAGVPLE ALAATINKIC SIALLSNATE SENAVNVTEM NYVLLTEGDN VTIPLLESDD
     LWSNPLFNDS HDTVILVTGW TSNINGSNKA IDTIYNAYRA RGGYNFVVID TSDYVDTLYT
     WSAFNTNDLG VELANGLKEL IKYLPVEKIH LIGHSLGAHI VGAAGRRFQD LTGQMIPRIT
     GLDPANPCFN EGEALSGICR GDAEFVDIIH SNSMVLGKRD PIGDVDFYPN GVVSVQPGCL
     NPSCSHARAW ELYAETVYPG QENNMLAVKC NSVLSLDTGA CPGKSIPLGF ACPRTAKGNY
     FLKTSDQTPF GKKSS
//
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