ID B0X945_CULQU Unreviewed; 1185 AA.
AC B0X945;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Myosin xv {ECO:0000313|EMBL:EDS42951.1};
GN Name=6049401 {ECO:0000313|EnsemblMetazoa:CPIJ016115-PA};
GN ORFNames=CpipJ_CPIJ016115 {ECO:0000313|EMBL:EDS42951.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS42951.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS42951.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ016115-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ016115-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS232519; EDS42951.1; -; Genomic_DNA.
DR RefSeq; XP_001866167.1; XM_001866132.1.
DR AlphaFoldDB; B0X945; -.
DR STRING; 7176.B0X945; -.
DR EnsemblMetazoa; CPIJ016115-RA; CPIJ016115-PA; CPIJ016115.
DR KEGG; cqu:CpipJ_CPIJ016115; -.
DR VEuPathDB; VectorBase:CPIJ016115; -.
DR VEuPathDB; VectorBase:CQUJHB005141; -.
DR eggNOG; KOG4229; Eukaryota.
DR HOGENOM; CLU_272522_0_0_1; -.
DR InParanoid; B0X945; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF709; UNCONVENTIONAL MYOSIN-XV; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT DOMAIN 1..286
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 162..184
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 465..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..490
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..890
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..991
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1185 AA; 132980 MW; 1355D44809F5C0ED CRC64;
MHVRQAEYLK ERLEWSALEW EDNLPVIHLL AKKPVGIFHL LDDESNFPRA NDLSFLEKCH
YNHALNELYS RPRIGAQEFG ITHYAGQVWY SVEGFLEKNR DALRMDVIEL LSSSSDPLVG
EMTKQLKAQR DIGKTLPRGV NGRFVTMKPR TPTVAARFSD SLQQLLQSMA KCNPWFVRCV
KPNNDKQALR MDMPCVLQQL RYLGMLDTIK IRQCGYPVRL RFQHFVERYK HMLRTPLPRG
TPYRELSRFV LESLPGTNTE GPDFQLGATR VFLRESLHRV LEAIRSEKLR LAAVIIQKNV
RGMLARKRMY RQQRGATAIQ KQWRGYRERK KYVSLKTGIV KAQAILLRSE NGSRSTHYRV
FPPSWLEWRA SSRLSDTALV LQLADGVMQT VAVDSWTTCE EAAALAISSL GIPNLGWTVV
IDDNGIFTDS SGLDYVLDLV SEKELCPAFP LARLTSDQLK CDTKNINLSP LEPDGSPKRP
QVPPPEPPSA KRLSDTQVQT LQGILTHSDS KVERNEIDPE YTRHMESLAR KSSHDAMSRN
KIHSEYFESD KSSRSRSLDD LLVSDTNEHM NVLTEPVSLK HRMANHYQSN DEITPLKEPQ
PRYVKSQYAG KRSAGSHSSK YMDRSEMSIR SSAMSDTSEA PSLASHVRRV RVPSQASDVD
QFLDDLFSPV LDGSLDELSD ARSLAASIRG STKCTVETAT QDYVGMVLSS IQPCATLSSL
NYGTGIYTAI KGGGTAHQPK NNSVSSFNSP PAVPPANPNS LLMMTSPSSS DVTIPTYHSN
VQVDNAARQQ QVQRAFLQSA MAQNIQIQQQ LIAQNQALQT LLIQQEAPTS STINNSSSKH
NASVSPSTPQ IFNRKSSMKK NEMIKNRKDS SSASLIPPPP PPPLPPPLEL KDPLEVRPFL
DPYGRAKTVR IGKWRWPPPQ DAAGGEVDEN FIQFKMRYAN RKNTPQSQSN SNIESPIGSP
TGIDWDEFEI DSQIMNPTIN AQNTPDQKSN QRVAKRSFDI GADRPTPNSV GKLKLSNEMR
QRLEQVTAGH SIRSTSTRSD RTERIPAKLE DTRRMILEQQ LGGVMSNRPV ADLPSVKTHV
QRMETDKRSP PKVWPSVRNI LEGAQLTTSV VLLDHPNYLD QNSIALVPCK CPIFLPPRWL
GFHDDLAGGM ETDRKPLTTA GWYPLPCKSS RPGTPVENRC TRAIL
//
