ID   B0XEF7_CULQU            Unreviewed;       146 AA.
AC   B0XEF7;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   SubName: Full=Paraplegin {ECO:0000313|EMBL:EDS25954.1, ECO:0000313|EnsemblMetazoa:CPIJ017561-PA};
GN   Name=6051614 {ECO:0000313|EnsemblMetazoa:CPIJ017561-PA};
GN   ORFNames=CpipJ_CPIJ017561 {ECO:0000313|EMBL:EDS25954.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS25954.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS25954.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ017561-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ017561-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; DS232826; EDS25954.1; -; Genomic_DNA.
DR   RefSeq; XP_001868029.1; XM_001867994.1.
DR   AlphaFoldDB; B0XEF7; -.
DR   STRING; 7176.B0XEF7; -.
DR   EnsemblMetazoa; CPIJ017561-RA; CPIJ017561-PA; CPIJ017561.
DR   KEGG; cqu:CpipJ_CPIJ017561; -.
DR   VEuPathDB; VectorBase:CPIJ017561; -.
DR   VEuPathDB; VectorBase:CQUJHB006063; -.
DR   eggNOG; KOG0731; Eukaryota.
DR   HOGENOM; CLU_1779253_0_0_1; -.
DR   InParanoid; B0XEF7; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR   PANTHER; PTHR43655:SF8; PARAPLEGIN; 1.
DR   Pfam; PF00004; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          73..106
FT                   /note="ATPase AAA-type core"
FT                   /evidence="ECO:0000259|Pfam:PF00004"
SQ   SEQUENCE   146 AA;  15880 MW;  F4D18FC1775CB5F7 CRC64;
     MDKFEEKLRQ VLAHLGIKDG VSMQFKRSGD ISGKILFTLV ATGVIIARLN WMRGIRKRSA
     PDRLGAKVPK CALLLGSPGS GKTLLAKAVA TKVQVPFLSL NGSDNNITNR GTQLCAQPEK
     KSERSLLLVV DLANGGKNRR QYSTAY
//