ID B1BZ15_9FIRM Unreviewed; 395 AA.
AC B1BZ15;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Sugar isomerase, AgaS family {ECO:0000313|EMBL:EDS75662.1};
GN ORFNames=CLOSPI_00172 {ECO:0000313|EMBL:EDS75662.1};
OS Thomasclavelia spiroformis DSM 1552.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Thomasclavelia.
OX NCBI_TaxID=428126 {ECO:0000313|EMBL:EDS75662.1, ECO:0000313|Proteomes:UP000004910};
RN [1] {ECO:0000313|EMBL:EDS75662.1, ECO:0000313|Proteomes:UP000004910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1552 {ECO:0000313|EMBL:EDS75662.1,
RC ECO:0000313|Proteomes:UP000004910};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium spiroforme (DSM 1552).";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDS75662.1, ECO:0000313|Proteomes:UP000004910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1552 {ECO:0000313|EMBL:EDS75662.1,
RC ECO:0000313|Proteomes:UP000004910};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-
CC phosphate + NH4(+); Xref=Rhea:RHEA:47680, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:28938, ChEBI:CHEBI:71674, ChEBI:CHEBI:138150;
CC Evidence={ECO:0000256|ARBA:ARBA00029292};
CC -!- SIMILARITY: Belongs to the SIS family. AgaS subfamily.
CC {ECO:0000256|ARBA:ARBA00007748}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDS75662.1}.
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DR EMBL; ABIK02000004; EDS75662.1; -; Genomic_DNA.
DR RefSeq; WP_004609369.1; NZ_DS562848.1.
DR AlphaFoldDB; B1BZ15; -.
DR STRING; 428126.CLOSPI_00172; -.
DR GeneID; 67386686; -.
DR eggNOG; COG2222; Bacteria.
DR HOGENOM; CLU_012520_0_0_9; -.
DR OrthoDB; 9779207at2; -.
DR Proteomes; UP000004910; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05010; SIS_AgaS_like; 1.
DR CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR InterPro; IPR035466; GlmS/AgaS_SIS.
DR InterPro; IPR035464; SIS_AgaS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR32502:SF3; D-GALACTOSAMINE-6-PHOSPHATE DEAMINASE AGAS-RELATED; 1.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51464; SIS; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:EDS75662.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004910};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 50..207
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 221..373
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 395 AA; 44068 MW; F42D20349FC7FB55 CRC64;
MTKTIFDINE AQMSETKSTY TLTEIYQQPV TWKKTCQQIA ELKDELKAFI NQVTAQDDYD
IILTGAGTSE FVGNTLFSYL NKKLNYKVKS YGTTDLVATP ENYLSRTKPT LLISFGRSGN
SPESIGAIDV AEEVCDNLYH LFVTCNKDGA LSKRANNNDH CFAINLTDET HDQSFAMTSS
FSNMYLATYL CFNLDNLDEA ISDVEKIIAA GQNFLDNQYS IAKEIVDSYD FKRIVYLGSN
ALKGISQESA LKMLELTAGE VVTMYDTPLG FRHGPKSIVD DDTLTVIYIS DNAYSRQYEV
DLIKEMSGQR KGNKIVAVMN GKCDEIKELV DYVVEFDIDG KFDNILLGFD YIILAQTVAV
LKSLAMGKTP DNPCPTGEVN RVVKGVTLYP YSKGE
//
