ID B1FH82_9BURK Unreviewed; 515 AA.
AC B1FH82;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Protein CyaE {ECO:0000256|PIRNR:PIRNR001892};
GN ORFNames=BamIOP4010DRAFT_3392 {ECO:0000313|EMBL:EDT03067.1};
OS Burkholderia ambifaria IOP40-10.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=396596 {ECO:0000313|EMBL:EDT03067.1, ECO:0000313|Proteomes:UP000005463};
RN [1] {ECO:0000313|EMBL:EDT03067.1, ECO:0000313|Proteomes:UP000005463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IOP40-10 {ECO:0000313|EMBL:EDT03067.1,
RC ECO:0000313|Proteomes:UP000005463};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L.,
RA Tiedje J., Richardson P.;
RT "Sequencing of the draft genome and assembly of Burkholderia ambifaria
RT IOP40-10.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: CyaE is necessary for transport of calmodulin-sensitive
CC adenylate cyclase-hemolysin (cyclolysin).
CC {ECO:0000256|PIRNR:PIRNR001892}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|PIRNR:PIRNR001892}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR001892}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613, ECO:0000256|PIRNR:PIRNR001892}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDT03067.1}.
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DR EMBL; ABLC01000085; EDT03067.1; -; Genomic_DNA.
DR RefSeq; WP_006752569.1; NZ_ABLC01000085.1.
DR AlphaFoldDB; B1FH82; -.
DR PATRIC; fig|396596.7.peg.4224; -.
DR Proteomes; UP000005463; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR028351; CyaE.
DR InterPro; IPR003423; OMP_efflux.
DR PANTHER; PTHR30026:SF20; OUTER MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR30026; OUTER MEMBRANE PROTEIN TOLC; 1.
DR Pfam; PF02321; OEP; 2.
DR PIRSF; PIRSF001892; CyaE; 1.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|PIRNR:PIRNR001892};
KW Cytolysis {ECO:0000256|PIRNR:PIRNR001892};
KW Hemolysis {ECO:0000256|PIRNR:PIRNR001892};
KW Membrane {ECO:0000256|PIRNR:PIRNR001892}; Signal {ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|PIRNR:PIRNR001892}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..515
FT /note="Protein CyaE"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002761323"
FT REGION 34..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 52288 MW; A2C1965BE8A71CC4 CRC64;
MRVPEPPAAS IAAAALATAV ALAGCATSSI DLAPDAPDRP WQPQTSVAGD IVPAPPLASA
QRAPHDYTLP ASPALASVSP PAALDAAHPY TLPELIDLAE STNPLTRIAW NDARNAALAV
GIAKAAYLPN LSATAMGAYQ TSHGSTSTIL GDASSNTTVH GTISALSLQW LLFDFGGRAA
RVEAAEQASV ASNVAFTAVH QQVIHDVTVA YYRYEAARSR AASAQQGLAN ADAILAASRA
RMKQGVGTVV ELAQSTQNRA QANLALVQAN GAQSDSYLAL VSALGISPLS KPSIAALPKR
PLPPALASSV DAIVSDAIAR RPDLQGAYAL EQANRAKIKA AEAAFMPKIF LSASTSYASG
GTAISALPAI GDQAPTVNLN GSRYGGGVFL GVTIPLYDGG LRSAVLMQAR NDAQSASARL
TRTKEEAVRQ VVAAQNAVQT SLASHDAAKA LVDAAQTSYD AALTAYRNGV GSVTDATIAQ
SQLLAARNAE VDSYAGALSA AAALALATGT IGSSQ
//
